Recruiting

Observational Study

Sponsor:

University of Minnesota

Code:

NCT05290610

Conditions

Epilepsy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Functional mapping

Study Details

Brief summary:

This is a single group prospective study to determine the feasibility for generating brain maps that localize cerebral functions and inter-regional information flow in partial epilepsy in adult patients.

Conditions

Epilepsy

Study ID

NCT05290610

Start date

Jun 1, 2022

Status verified date

Apr, 2026

Completion date

Sep 1, 2027

Anticipated

Primary completion date

Jun 1, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Male or female 18 years and older at screening.
  • Written informed consent is obtained from the participant to comply with the requirements of the study.
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Currently undergoing clinically indicated intracranial EEG monitoring for planning of epilepsy surgery in the University of Minnesota/MINCEP program.

Exclusion Criteria:

  • Pregnancy ruled out prior to approval for intracranial EG monitoring.
  • Persons who are rendered temporarily or permanently invulnerable by inability to understand the research due to study complexity, cognitive impairment, or by inability to make independent decisions owing to University of Minnesota or to Fairview health services.

Study Design

Enrollment

30 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

other: Research IESM

Functional mapping for research application

Interventions

Functional mapping

Intracranial EEG data acquisition, observation and behavioral testing, and intracranial electrical stimulation

Primary outcome measure

  • The effect of prefrontal direct electrical brain stimulation on cognitive effort [ Time Frame: Immediately after stimulation sessions ]

Central Contacts and Locations

Central contacts

Matthew Maple

612-946-1424maple036@umn.edu

Locations

University of Minnesota

Recruiting

Minneapolis, Minnesota, United States, 55455

Contacts

Alexander Herman, MD, PhD

612-625-1194herma686@umn.edu

More Information

Sponsor

University of Minnesota

Last update posted

Apr 9, 2026

Last verified

Apr, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Minnesota on 2026-04-09.