Recruiting

eSCCIP

Sponsor:

Nemours Children's Clinic

Code:

NCT05294302

Conditions

Pediatric Cancer

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

eSCCIP/eSCCIP-SP

Coping Space

Study Details

Brief summary:

It is critical to provide accessible evidence-based psychosocial support to parents and caregivers of children with cancer (PCCC) in order to mitigate individual and family-level psychosocial risks. This effectiveness trial evaluates an eHealth intervention for English- and Spanish-speaking (PCCC) with study endpoints focused on decreasing negative psychosocial sequelae (acute distress, posttraumatic stress, and anxiety) and improving coping abilities (coping self-efficacy, cognitive coping strategies). The long-term goal of this research program is to sustain and disseminate an effective, scalable, high-reach, and cost-effective intervention to provide crucial support to PCCC across the pediatric cancer trajectory.

Conditions

Pediatric Cancer

Study ID

NCT05294302

Start date

Apr 14, 2023

Status verified date

Jul, 2026

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Participants must be the parent or primary caregiver of a child (ages 0 - 18 years old) diagnosed with cancer.
  • Participants must be able to speak and read English or Spanish.
  • Participants must have access to the internet through a computer or mobile device (e.g., smartphone, tablet).

Exclusion Criteria:

  • PCCC are ineligible to participate if their child is not expected to live longer than six months from the time of potential recruitment

Study Design

Enrollment

350 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

active comparator: eSCCIP/eSCCIP-SP

The Electronic Surviving Cancer Competently Intervention Program (eSCCIP) is an innovative eHealth intervention that combines cognitive behavioral and family systems therapy to provide parents and caregivers of children with cancer (PCCC) with evidence-based coping skills and psychosocial support focused on the family unit. eSCCIP has three 30-minute, self-directed, online modules which feature a unique mix of original video content and interactive activities, supplemented by three telehealth follow-up sessions. A stakeholder-informed Spanish-language adaption of eSCCIP (eSCCIP-SP) has been developed and will be offered to Spanish-speaking PCCC. eSCCIP aims to reduce acute distress and symptoms of post-traumatic stress while increasing positive coping self-appraisal and use of cognitive coping skills.

active comparator: Coping Space

PCCC randomized to the patient education control condition will be given access to a website with information about psychosocial functioning, coping, and PTSS related to pediatric cancer. This website will be hosted on the same platform as the intervention, available in English and Spanish, and will consist of information modified from CopingSpace.org. CopingSpace.org is an evidence-informed website developed by Ryan's Case for Smiles, a national organization dedicated to supporting families impacted by pediatric cancer and other chronic diseases.

Interventions

eSCCIP/eSCCIP-SP

eSCCIP/eSCCIP-SP is a psychosocial eHealth intervention for PCCC. It consists of four self-guided, web-based modules (including an introductory module) and three telehealth sessions with a study interventionist.

Coping Space

Coping Space is a psychosocial informational website for PCCC.

Primary outcome measure

  • K-6 [ Time Frame: Up to 20 weeks ]

Central Contacts and Locations

Central contacts

Kimberly Canter, Ph.D.

3026514501kimberly.canter@nemours.org

Locations

Nemours Children's Health, Delaware

Recruiting

Wilmington, Delaware, United States, 19803

Contacts

Kimberly Canter

3026514501kimberly.canter@nemours.org

More Information

Sponsor

Nemours Children's Clinic

Last update posted

Jul 17, 2026

Last verified

Jul, 2026

Keywords

  • eHealth
  • pediatric cancer
  • parents
  • psychosocial intervention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Nemours Children's Clinic on 2026-07-17.