Recruiting

Supportive Cancer Care

Sponsor:

Stanford University

Code:

NCT05297734

Conditions

End of Life

Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Receive technology-based supportive cancer care

Receive redesigned team-based supportive cancer care

Study Details

Brief summary:

This cluster-randomized comparative effectiveness trial compares a technology-based supportive cancer care (SCC) approach with a redesigned team-based supportive cancer care (SCC) approach.

Conditions

End of Life

Cancer

Study ID

NCT05297734

Start date

Jun 24, 2022

Status verified date

Apr, 2026

Completion date

Feb 28, 2028

Anticipated

Primary completion date

Jan 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Newly diagnosed patients with solid tumor cancer diagnosis or recurrence of the disease.
2. Patients must have the ability to understand and willingness to provide verbal consent.
3. Participants must speak English, Spanish, Chinese, or Vietnamese.

Exclusion Criteria:

1. Inability to consent to the study
2. Plans to change oncologist within 12 months
3. Employed by the practice site
4. Patients who anticipate moving from the area within 12 months

Study Design

Enrollment

2996 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

active comparator: Technology-based supportive cancer care

Patients receive educational materials to assist with advance care planning and symptom management through a technology-based supportive cancer care weekly during months 1-4 and every other week during months 5-12.

experimental: Redesigned team-based supportive cancer care

Patients are paired with a health educator who will discuss the same educational materials from ARM A either in person or by telephone discussions weekly during months 1-4 and every other week during months 5-12.

Interventions

Receive technology-based supportive cancer care

All participants will receive an electronic health record message or email with standardized information provided regarding advance care planning and symptom management.

Receive redesigned team-based supportive cancer care

Lay Health Workers will meet with 1:1 with participants over 12 months to discuss advance care planning, surrogate decision-makers, advance directives and physician orders for life sustaining treatment.

Primary outcome measure

  • Change in health-related quality of life as assessed by the Functional Assessment of Cancer Therapy (FACT-G). [ Time Frame: Change in health-related quality of life from baseline to 3 months ]

Central Contacts and Locations

Central contacts

Manali I Patel, MD MPH MS

6507234000manalip@stanford.edu

Locations

University of Alabama at Birmingham

Recruiting

Birmingham, Alabama, United States, 35294

University of South Alabama

Recruiting

Mobile, Alabama, United States, 36688

Beckman Research Institute of City of Hope

Recruiting

Duarte, California, United States, 91010

Contacts

Finly Zachariah, MD

800-826-4673

VA Medical Center, Fresno

Recruiting

Fresno, California, United States, 93703

Santa Clara Valley Medical Center

Recruiting

Fruitdale, California, United States, 95128

St Jude Heritage Medical Group

Recruiting

Fullerton, California, United States, 92835

Oncology Institute for Hope and Innovation

Recruiting

Los Angeles, California, United States, 90017

Zuckerberg San Francisco General

Recruiting

San Francisco, California, United States, 94110

Kaiser Foundation Research Institute

Recruiting

San Francisco, California, United States, 94115

University of San Francisco

Recruiting

San Francisco, California, United States, 94117

Spark M. Matsunaga VA Medical Center

Recruiting

Honolulu, Hawaii, United States, 96819

George E. Wahlen Department of Veterans Affairs Medical Center

Recruiting

Salt Lake City, Utah, United States, 84148

More Information

Sponsor

Stanford University

Last update posted

Apr 30, 2026

Last verified

Apr, 2026

Keywords

  • Carcinoma
  • Lung Neoplasms
  • Carcinoma, Non-Small-Cell Lung
  • Melanoma
  • Pancreatic Neoplasms
  • Sarcoma
  • Ovarian Neoplasms
  • Carcinoma, Ovarian Epithelial
  • Stomach Neoplasms
  • Glioblastoma
  • Rectal Neoplasms
  • Colonic Neoplasms
  • Esophageal Neoplasms
  • Breast Neoplasms
  • Carcinoma, Renal Cell
  • Skin Neoplasms
  • Small Cell Lung Carcinoma
  • Osteosarcoma
  • Myelodysplastic Syndromes
  • Disease Progression
  • Neoplasms, Glandular and Epithelial
  • Neoplasms by Histologic Type
  • Neoplasms
  • Respiratory Tract Neoplasms
  • Thoracic Neoplasms
  • Neoplasms by Site
  • Lung Diseases
  • Respiratory Tract Diseases
  • Urogenital Neoplasms
  • Carcinoma, Bronchogenic

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Stanford University on 2026-04-30.