Recruiting

Observational Study

Sponsor:

Baylor University

Code:

NCT05298956

Conditions

Stress Reaction

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Interventions

Low-level laser therapy (LLLT)

Study Details

Brief summary:

Transcranial infrared laser stimulation is a non-invasive neuromodulation technique. The study will examine the effect of transcranial infrared laser stimulation on cardiovascular and metabolic responses to stress.

Conditions

Stress Reaction

Study ID

NCT05298956

Start date

Mar 14, 2022

Status verified date

Jul, 2023

Completion date

Aug, 2024

Anticipated

Primary completion date

Aug, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 30

Healthy Volunteers: Accepted

Inclusion Criteria:

18-30 years old

Exclusion Criteria:

History of a diagnosed chronic medical or neurological disorder Current pregnancy Current illness or infection (e.g., cold, flu) Any condition that would prohibit them from engaging in physical exercise

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

sham comparator: Sham

Participants will receive sham laser to the right forehead.

active comparator: Transcranial infrared laser stimulation

Participants will receive transcranial infrared laser stimulation to the right forehead.

Interventions

Low-level laser therapy (LLLT)

Sham Comparator: Participants will receive 8 counts of 60 seconds of the same laser to the right forehead, however the laser power will be turned off and will be 0 Watts.

Transcranial infrared laser stimulation: Participants will receive 8 counts of 60 seconds of transcranial infrared laser stimulation to the right forehead. The wavelength will be 1064 nm and the laser power will be 3.4 Watts.

Primary outcome measure

  • Oxygen consumption in response to acute psychological stress [ Time Frame: Immediately following intervention (up to 60 minutes) ]
  • Heart rate in response to acute psychological stress [ Time Frame: Immediately following intervention (up to 60 minutes) ]
  • Additional heart rate in response to acute psychological stress [ Time Frame: Immediately following intervention (up to 60 minutes) ]

Central Contacts and Locations

Locations

Annie T. Ginty

Recruiting

Waco, Texas, United States, 76798

Contacts

Annie T. Ginty, PhD

254-710-2236annie_ginty@baylor.edu

More Information

Sponsor

Baylor University

Last update posted

Aug 1, 2023

Last verified

Jul, 2023

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Baylor University on 2023-08-01.