Recruiting
Phase 1

Tazemetostat, Topotecan, Pembrolizumab

Sponsor:

National Cancer Institute (NCI)

Code:

NCT05353439

Conditions

Extensive Stage Lung Small Cell Carcinoma

Limited Stage Lung Small Cell Carcinoma

Platinum-Resistant Lung Small Cell Carcinoma

Platinum-Sensitive Lung Small Cell Carcinoma

Recurrent Extensive Stage Lung Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy Procedure

Biospecimen Collection

Computed Tomography

Pembrolizumab

Tazemetostat Hydrobromide

Study Details

Eligibility Criteria

Study Design

Interventions and Outcome Measures

Central Contacts and Locations

More Information

Trial information was received from ClinicalTrials.gov and was last updated on 2025-12-14. This information was provided to ClinicalTrials.gov by National Cancer Institute (NCI) on 2025-11-25.