Recruiting

Observational Study

Sponsor:

Northwestern University

Code:

NCT05358483

Conditions

Infertility, Female

Eligibility Criteria

Sex: Female

Age: 18 - 44

Healthy Volunteers: Accepted

Study Details

Brief summary:

The goal of the PROMISE study is to determine how pre-conception lifestyle factors (e.g., sleep, nutrition, physical activity) affect short- and long-term reproductive outcomes.

Conditions

Infertility, Female

Study ID

NCT05358483

Start date

Sep 7, 2021

Status verified date

Jun, 2026

Completion date

Dec, 2046

Anticipated

Primary completion date

Dec, 2046

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18 - 44

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Women ages 18-44 seeking pregnancy at Northwestern Fertility and Reproductive Medicine (FRM) who agree to

1. Be followed for a period for up to 25 years
2. Share information regarding their child's health
  • No prior IVF cycles

Exclusion Criteria:

  • Women using donor oocytes or gestational carriers
  • Inability or unwillingness to provide informed consent for any aspects of the study

Study Design

Enrollment

1000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Live birth after embryo transfer [ Time Frame: ~0-24 months ]

Central Contacts and Locations

Central contacts

Emily Jungheim, MD, MSCI

312-926-6643Emily.Jungheim@nm.org

Brianna Borger, BS

312-503-8208Brianna.Borger1@nm.org

Locations

Northwestern Medicine Fertility and Reproductive Medicine

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Emily Jungheim, MD, MSCI

Emily.Jungheim@nm.org

Brianna Borger, BS

312-503-8208Brianna.Borger1@nm.org

More Information

Sponsor

Northwestern University

Last update posted

Jun 16, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Northwestern University on 2026-06-16.