Recruiting

Power Prenatal

Sponsor:

The Bird and Be Co Inc

Code:

NCT05410782

Conditions

Spermatogenesis and Semen Disorders

Infertility, Male

Eligibility Criteria

Sex: Male

Age: 18 - 45

Healthy Volunteers: Accepted

Interventions

Power Prenatal for Sperm

Study Details

Brief summary:

Male factor infertility is a leading cause of primary and secondary infertility. Poor sperm quality is defined as having an abnormal semen analysis \[WHO 2020 - https://www.who.int/publications/i/item/9789240030787\]. The effects of supplements (vitamins, minerals, and anti-oxidants) on improving sperm quality are still debated (https://pubmed.ncbi.nlm.nih.gov/30462179). Taking additional supplements to improve sperm quality represent a modifiable risk-factor that would be an easy intervention for patients struggling with male factor infertility. The life cycle of sperm production is estimated at 3 months, so any intervention would require a 3 month course to see its full effect.

The investigators hypothesize that a 90 day course of the "Power Prenatal for Sperm", a male fertility supplement by Bird\&Be (https://birdandbe.com/the-power-prenatal-for-sperm) will improve sperm quality based on semen analysis results prior to, and after taking the supplements.

Conditions

Spermatogenesis and Semen Disorders

Infertility, Male

Study ID

NCT05410782

Start date

Nov 1, 2023

Status verified date

Aug, 2024

Completion date

Dec 31, 2026

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18 - 45

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Male
  • Age 18-45 years old
  • Experiencing infertility
  • A recent semen analysis confirming low count, motility or morphology (at least 1 of 3) - within last 3 months

1. Low concentration: < 15 Million / mL
2. Low Motility: Progessive Motility < 30%
3. Morphology: Strict criteria: Normal forms < 4% Reference: WHO 2020 6th edition: https://www.who.int/publications/i/item/9789240030787

Exclusion Criteria:

  • No diagnosed varicocele
  • Younger than 18 years old
  • Older than 45 years old
  • Currently taking any form of antioxidant supplements(in last 3 months) besides a general multivitamin

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Power Prenatal for Sperm

This is a single arm study. Participants will take supplements for 3 months. The supplements is Power Prenatal for Sperm (active ingredients - https://birdandbe.com/the-power-prenatal-for-sperm)

Interventions

Power Prenatal for Sperm

A prenatal vitamin complex that includes numerous ingredients aim at improving sperm quality (ingredients: https://birdandbe.com/the-power-prenatal-for-sperm)

Primary outcome measure

  • Sperm Progressive Motility (Semen Analysis); as percentage (%) [ Time Frame: A repeat semen analysis will be performed 3 months after Power Prenatal for Sperm intervention ]

Central Contacts and Locations

Central contacts

Dan Nayot, Bsc, MSc, MD

4166163334dan@birdandbe.com

Locations

Reproductive Care Centre

Recruiting

Mississauga, Ontario, Canada, L5N 5S3

Contacts

Dan Nayot, BSc, MSc, MD

905-816-9822dnayot@rccfertility.com

More Information

Sponsor

The Bird and Be Co Inc

Last update posted

Apr 8, 2025

Last verified

Aug, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by The Bird and Be Co Inc on 2025-04-08.