Recruiting

Observational Study

Sponsor:

University of Louisville

Code:

NCT05419713

Conditions

Vision

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Interventions

Visual Stimuli for Space Perception

Study Details

Brief summary:

The ability to judge the locations of various objects from oneself during self-motion in the intermediate distance range (\~2-25m) is crucial for successful performance of activities of daily living, such as walking and driving. However, little is known about the mechanisms of visual space perception involved in judging distance, the focus of this project, in the planning and/or execution of self-motion in the natural 3D environment. The theoretical knowledge to be gained from this project will contribute to the scientific literature and provide insights into how eye and neurological defects could impair visual space perception, wayfinding, and mobility.

Conditions

Vision

Study ID

NCT05419713

Start date

Sep 30, 2021

Status verified date

Sep, 2025

Completion date

Jun 30, 2026

Anticipated

Primary completion date

Jun 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 40

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Adults (up to 40 years of age)
  • Children (18 years and older)
  • Normal, or corrected-to-normal, visual acuity (at least 20/20)
  • Stereo acuity (<20 arc sec).

Exclusion Criteria:

  • Self-reported history of visual and eye diseases
  • Physical movement restrictions.
  • Vulnerable populations such as pregnant women will be excluded owing to the extensive time commitment required of the subjects.

Study Design

Enrollment

180 participants

Anticipated

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Visual scences

Lit target locations in visual environment will be varied and subjects' perceived locations will be measured.

Interventions

Visual Stimuli for Space Perception

The visual environment (e.g., target locations and texture backgrounds) will be varied and human behavioral responses (judged distances) will be measured to reveal the space perception and cognitive processes underlying space perception and navigation.

Primary outcome measure

  • Visual mechanisms of intermediate distance space perception (distance) before and after self-motion [ Time Frame: During procedure, an average of 10 sec. ]
  • Visual mechanisms of intermediate distance space perception (height) before and after self-motion. [ Time Frame: Druing procedure, an average of 10 sec. ]

Central Contacts and Locations

Central contacts

Zijiang He, Ph.D.

502-852-6779zjhe@louisville.edu

Locations

University of Louisville

Recruiting

Louisville, Kentucky, United States, 49292

Contacts

Zijiang He, Ph.D.

5028526779zjhe@louisville.edu

Principal Investigator:

Zijiang He, Ph.D.

More Information

Sponsor

University of Louisville

Last update posted

May 7, 2026

Last verified

Sep, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Louisville on 2026-05-07.