Recruiting

Observational Study

Sponsor:

Francis Farhadi

Code:

NCT05446259

Conditions

Cervical Myelopathy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Standard clinical care procedures and outcome measurements.

Study Details

Brief summary:

To create a research repository of patients with known degenerative cervical myelopathy (DCM) and a control cohort of subjects who have non-myelopathic spinal disease. This repository will be used to assess functional and/or biological measures that may allow for improved prediction of symptomatic progression and response to treatment in patients with DCM. In addition, this repository will be used to develop a risk assessment scale to accurately predict functional outcomes following operative management of DCM.

Conditions

Cervical Myelopathy

Study ID

NCT05446259

Start date

Jul 13, 2022

Status verified date

Feb, 2026

Completion date

May, 2028

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosis of degenerative cervical myelopathy
  • Diagnosis of cervical degenerative disease without myelopathy

Exclusion Criteria:

  • None outside or diagnostic requirements and age limits.

Study Design

Enrollment

245 participants

Anticipated

Interventions and Outcome Measures

Arms

DCM group

Subjects diagnosed with degenerative cervical myelopathy.

Control group

Subjects diagnosed with cervical spinal disease without myelopathic symptoms.

Interventions

Standard clinical care procedures and outcome measurements.

Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.

Primary outcome measure

  • Data comparison between DCM and control groups [ Time Frame: 2 years ]

Central Contacts and Locations

Central contacts

Francis Farhadi, MD, PhD

859-562-0247francis.farhadi@uky.edu

Harshit Arora, PhD

859-323-4533harshit.arora@uky.edu

Locations

University of Kentucky

Recruiting

Lexington, Kentucky, United States, 40536

Contacts

Francis Farhadi, MD, PhD

859-562-0247francis.farhadi@uky.edu

Harshit Arora, PhD

859-323-4533harshit.arora@uky.edu

More Information

Sponsor

Francis Farhadi

Last update posted

Feb 13, 2026

Last verified

Feb, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-08. This information was provided to ClinicalTrials.gov by Francis Farhadi on 2026-02-13. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.