Recruiting

Observational Study

Sponsor:

Milton S. Hershey Medical Center

Code:

NCT05447806

Conditions

Hyperglycemia

Hyperglycemia Stress

Diabetes

PreDiabetes

Hypoglycemia

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Active Electronic Medical Record Inpatient Diabetes Clinical Decision Support

Study Details

Brief summary:

The purpose of this study is to determine the impact of an electronic medical record clinical decision support tool on rates of dysglycemia in the hospital, and its clinical and economical outcomes. The study also evaluates the perspectives of providers regarding the tool's usefulness on disease management support, knowledge, and practice performance.

Conditions

Hyperglycemia

Hyperglycemia Stress

Diabetes

PreDiabetes

Hypoglycemia

Study ID

NCT05447806

Start date

Jul 15, 2022

Status verified date

Aug, 2025

Completion date

Oct 16, 2026

Anticipated

Primary completion date

Oct 16, 2025

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Hospitalized adult (>18 years) patients at Penn State Health, Hershey Medical Center, St. Joseph's Hospital, Hampden Medical Center, Holy Spirit Medical Center, and Lancaster Medical Center
  • Ambulatory adult (>18 years) patients at Penn State Health, Hershey Medical Center, St. Joseph's Hospital, Hampden Medical Center, Holy Spirit Medical Center, and Lancaster Medical Center
  • Trigger of an alert or a disease management message

Exclusion Criteria:

  • Children (<18 years)

Study Design

Enrollment

15732 participants

Anticipated

Allocation

Non randomized

Intervention Model

Parallel Assignment

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

experimental: Active Inpatient Diabetes Clinical Decision Support

The Active arm consists of participants treated during the "ON" phase of the GlucAlert-CDS tool. The tool operates through an automated process of rules embedded in the EMR recognizing hypoglycemia (established or impending); recurrent hyperglycemia (in type 1 and 2 DM, or stress hyperglycemia-SH); and inappropriate insulin use (sliding scales monotherapy if recurrent hyperglycemia in type 2 DM or SH, or any time in type 1 DM). If the tool's criteria are met, an alert in the EMR will notify the provider with the clinically recommended treatment.

no intervention: Inactive Inpatient Diabetes Clinical Decision Support

The Inactive arm consists of participants treated during the "OFF" phase of the GlucAlert-CDS Tool. Alerts will not be sent to provider's

Interventions

Active Electronic Medical Record Inpatient Diabetes Clinical Decision Support

This prospective intervention will be carried out over 36 months and encompass 12 alternating GlucAlert-CDS phases lasting 3 months each. Six active phases (ON period) and six inactive phases (OFF period) will represent 18 months of intervention and control respectively. GlucAlert-CDS recognizes gaps in care denoting the automatic process of subjects' identification and inclusion. During the ON period, gap in care events detected in patients' EMR will evoke alert messages and care recommendations for clinicians in real time for their consideration. These notifications are programmed to be delivered to primary inpatient providers in direct care of these hospitalized patients. During the OFF period, the program will record the gaps in care events detected, but alerts will be inactive for providers' viewing.

Primary outcome measure

  • Average hospital length of stay (LOS) [ Time Frame: Duration of hospital admission, up to 3 months ]

Central Contacts and Locations

Central contacts

Ariana Pichardo-Lowden, MD

7175310003apichardolowden@pennstatehealth.psu.edu

Locations

Penn State Hershey Medical Center

Recruiting

Hershey, Pennsylvania, United States, 17033

Contacts

Ariana Pichardo-Lowden, MD

717-531-0003apichardolowden@pennstatehealth.psu.edu

Penn State Health St. Joseph Medical Center

Recruiting

Reading, Pennsylvania, United States, 19605

Contacts

Franciss Quigley, MD

610 378 2440fquigley@pennstatehealth.psu.edu

More Information

Sponsor

Milton S. Hershey Medical Center

Last update posted

May 14, 2026

Last verified

Aug, 2025

Keywords

  • Clinical Decision Support
  • Electronic Medical Records
  • Health Systems Science
  • Hospital Management

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Milton S. Hershey Medical Center on 2026-05-14.