Recruiting

Observational Study

Sponsor:

St. Jude Children's Research Hospital

Code:

NCT05454618

Conditions

Knowledge, Attitudes, Practice

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The focus of this study is to learn about the factors that parents consider when making a decision for their child to participate or not in a clinical treatment research study.

Conditions

Knowledge, Attitudes, Practice

Study ID

NCT05454618

Start date

Oct 4, 2022

Status verified date

May, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • All English or Spanish speaking parents/LARs of patients 0-18 years of age with newly diagnosed cancer in the Affiliate network.

Exclusion Criteria:

  • Parents of children with relapsed or recurrent disease, or those with benign neoplasms.

Study Design

Enrollment

400 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Sociodemographic characteristics of patients treated through the Affiliate network [ Time Frame: Day 1, or during a future contact (approximately 1 month) ]
  • The correlation between social determinants and individual preferences among parents/LARs and the decision to enroll on a therapeutic clinical trial. [ Time Frame: Day 1, or during a future contact (approximately 2 months) ]
  • The correlation between social determinants, decision-making factors, trial related attitudes among parents/LARs and the decision to enroll or not enroll on a therapeutic clinical trial. [ Time Frame: Approximately 3 months after enrollment ]
  • Differences between parent/LAR individual preferences as expressed to parent interviewers compared to non-parent interviewers [ Time Frame: Approximately 3 months after enrollment ]
  • Acceptability of a parent navigator program in the Affiliate network [ Time Frame: After initiation of the Parent Navigator Program approximately 4 years after start of study ]
  • Feasibility of a parent navigator program in the Affiliate network [ Time Frame: After initiation of the Parent Navigator Program approximately 4 years after start of study ]

Central Contacts and Locations

Central contacts

Dylan Graetz, MD

888-226-4343referralinfo@stjude.org

Locations

St. Jude Children's Research Hospital

Recruiting

Memphis, Tennessee, United States, 38105

Contacts

Dylan Graetz, MD

888-226-4343referralinfo@stjude.org

Principal Investigator:

Dylan Graetz, MD

More Information

Sponsor

St. Jude Children's Research Hospital

Last update posted

May 20, 2026

Last verified

May, 2026

Keywords

  • Parent
  • Pediatric Oncology Patients
  • Caregivers
  • Barriers to Enrollment on a Therapeutic Trial
  • Parent Navigator Program
  • Affiliate Network
  • Decision Making
  • Healthcare
  • Parent Engagement

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by St. Jude Children's Research Hospital on 2026-05-20.