Recruiting

Quadriceps Tendon vs. Bone Patellar Tendon

Sponsor:

University of Alabama at Birmingham

Code:

NCT05461326

Conditions

Orthopedic Disorder

Anterior Cruciate Ligament Injuries

Eligibility Criteria

Sex: All

Age: 14 - 65

Healthy Volunteers: Not accepted

Interventions

Quad tendon

BTB

Study Details

Brief summary:

The choice of autograft for ACL reconstruction continues to be debated. To date, there has only be one completed randomized controlled trial with quad tendon to BTB and the tendon included a bone plug. There has been no study to date comparing an all soft tissue quad tendon to patellar tendon in a randomized controlled trial for ACL reconstruction.

Conditions

Orthopedic Disorder

Anterior Cruciate Ligament Injuries

Study ID

NCT05461326

Start date

Sep 26, 2023

Status verified date

Jun, 2026

Completion date

Jun 30, 2030

Anticipated

Primary completion date

Jun 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 14 - 65

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Skeletally mature patients younger 65
  • ACL insufficiency
  • Scheduled to undergo autograft ACL reconstruction
  • Appropriate candidate for autograft harvest

Exclusion Criteria:

  • <14 or 65>
  • Poor autograft candidate (poor tissue quality)
  • Multi ligamentous reconstruction (PCL, MCL, or PLC)
  • Pregnant or nursing
  • High likelihood of remaining non-compliant with physical therapy regimen
  • Desire to return to sport prior to 6 months
  • Inability to read and write English

Study Design

Enrollment

100 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Quad tendon

ACL graft harvested from the quadriceps tendon

active comparator: BTB tendon

ACL graft harvested from the patellar tendon

Interventions

Quad tendon

quadriceps tendon autograft

BTB

patellar tendon autograft

Primary outcome measure

  • KT-1000 Arthrometer [ Time Frame: Operative Day, 9 Months Post-Operative Clinic Visit ]

Central Contacts and Locations

Central contacts

Amit Momaya, MD

864-436-0621amomaya@uabmc.edu

Locations

UAB Hospital Highlands

Recruiting

Birmingham, Alabama, United States, 35205

Contacts

Amit Momaya, MD

(205)-930-8339amomaya@uabmc.edu

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Jun 10, 2026

Last verified

Jun, 2026

Keywords

  • quadriceps tendon
  • bone tendon bone
  • autograft

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2026-06-10.