Recruiting

Biomarkers RepositoryCirculating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

Sponsor:

Duke University

Code:

NCT05480644

Conditions

Brain Tumor, Primary

Brain Metastases, Adult

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this protocol is to create a repository of blood samples from patients diagnosed with primary and metastatic brain tumors who are being seen in the Department of Radiation Oncology at Duke Cancer Center.

Conditions

Brain Tumor, Primary

Brain Metastases, Adult

Study ID

NCT05480644

Start date

Dec 1, 2022

Status verified date

Nov, 2025

Completion date

Dec, 2032

Anticipated

Primary completion date

Dec, 2032

Anticipated

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)

Exclusion Criteria:

None

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

Number of circulating immune cells in peripheral blood [ Time Frame: 6 weeks post radiation therapy ]

Central Contacts and Locations

Central contacts

Kaitlin Bailey, RN OCN

(919) 668-3726 Kaitlin.Bailey@duke.edu

Linda Kaltenbach, PhD

Linda.Kaltenbach@duke.edu

Locations

Duke Cancer Center

Recruiting

Durham, North Carolina, United States, 27710

Contacts

Kaitlin Bailey, RN

919-668-3726 Kaitlin.Bailey@duke.edu

Linda Kaltenbach, PhD

Linda.Kaltenbach@duke.edu

Principal Investigator:

Eugene Vaios, MD MBA

More Information

Sponsor

Duke University

Last update posted

Nov 19, 2025

Last verified

Nov, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Duke University on 2025-11-19.