Recruiting

Observational Study

Sponsor:

University Health Network, Toronto

Code:

NCT05485649

Conditions

Epilepsy

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The aim of this study is to investigate the pregnancy, delivery, neonatal, and epilepsy outcomes in individuals with epilepsy undergoing pregnancy at the Maternal and Infant Health Programs at the University Health Network - Sinai Health and followed for epilepsy at the Toronto Western Hospital Epilepsy Clinic. In particular, we are interested in the association between following recommended epilepsy management guidelines for pregnant individuals with epilepsy and those aforementioned outcomes.

Conditions

Epilepsy

Study ID

NCT05485649

Start date

Jul 20, 2022

Status verified date

Apr, 2026

Completion date

Aug, 2026

Anticipated

Primary completion date

Jun, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. WWE seen at the Toronto Western Hospital Epilepsy Clinic since June 1st 2022.
2. Pregnant at any point between June 1st 2022 and June 1st 2024 (period of enrolment).
3. Diagnosed with epilepsy as per the International League Against Epilepsy (ILAE) 2014 definition of epilepsy.

Exclusion Criteria:

  • None

Study Design

Enrollment

80 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Frequency of adherence to the 2015 Ontario Task Force management of epilepsy in pregnancy [ Time Frame: 2 years ]

Central Contacts and Locations

Central contacts

Esther Bui, MD

416-603-5320Esther.Bui@uhn.ca

Sharon Ng, BA

416-603-5320Sharon.Ng@uhnresearch.ca

Locations

University Health Network

Recruiting

Toronto, Ontario, Canada, M5T 2S8

Contacts

Esther Bui, MD

416-603-5320Esther.Bui@uhn.ca

More Information

Sponsor

University Health Network, Toronto

Last update posted

May 6, 2026

Last verified

Apr, 2026

Keywords

  • Pregnancy
  • Neonatal
  • Obstetrical
  • Anti-seizure medication

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University Health Network, Toronto on 2026-05-06.