Recruiting

Neuromodulation

Sponsor:

University of Oklahoma

Code:

NCT05487131

Conditions

Healthy Aging

Fatigue

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Interventions

electrical stimulation

Study Details

Brief summary:

In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by up to 6 experimental sessions. Fatigability and motor function will be assessed in each test session.

Conditions

Healthy Aging

Fatigue

Study ID

NCT05487131

Start date

Jun 3, 2023

Status verified date

Apr, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Sep, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 50

Healthy Volunteers: Accepted

Inclusion Criteria:

Healthy individuals between 18 and 50 years old

Exclusion Criteria:

Metal implants or joint replacement. Presence of neuromuscular disease. Skin hypersensitivity.

Study Design

Enrollment

40 participants

Anticipated

Allocation

Randomized

Intervention Model

Single group

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

experimental: Men

Individuals will participate in 1 familiarization and up to 6 test sessions

experimental: Women

Individuals will participate in 1 familiarization and up to 6 test sessions

Interventions

electrical stimulation

different types of low-intensity (comfortable) electrical stimulation will be used and applied in distinct locations

Primary outcome measure

  • Force [ Time Frame: Each session will take approximately 2 hours (total of 4 test sessions) ]
  • Perception of effort [ Time Frame: Each session will take approximately 2 hours (total of 4 test sessions) ]
  • Muscle activation [ Time Frame: Each session will take approximately 2 hours (total of 4 test sessions) ]

Central Contacts and Locations

Central contacts

Hugo Pereira, PhD

405-325-2773hugomax@ou.edu

Locations

University of Oklahoma

Recruiting

Norman, Oklahoma, United States, 73071

Contacts

Hugo Pereira, PhD

405-325-2773hugomax@ou.edu

More Information

Sponsor

University of Oklahoma

Last update posted

Apr 9, 2026

Last verified

Apr, 2026

Keywords

  • Transcutaneous spinal direct current stimulation
  • TsDCS
  • Fatigability

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Oklahoma on 2026-04-09.