Recruiting

Sex Selection

Sponsor:

Weill Medical College of Cornell University

Code:

NCT05500573

Conditions

Infertility

IVF

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Sperm Sorting

Study Details

Brief summary:

This study aims to demonstrate a reliable method of selecting gender specific sperm. X-bearing spermatozoa and Y-bearing spermatozoa will be identified from the density gradient layers. The selected gender specimen will then be utilized for assisted reproductive fertilization- in vitro fertilization or intrauterine insemination which are routine standard of care procedures.

Conditions

Infertility

IVF

Study ID

NCT05500573

Start date

Nov 6, 2013

Status verified date

May, 2026

Completion date

Dec 31, 2029

Anticipated

Primary completion date

Dec 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Couples undergoing infertility treatment with IVF or insemination seeking gender specific offspring for medical and non medical reasons

Exclusion Criteria:

  • Severe male factor

Study Design

Enrollment

2000 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Sperm sorting

Selection of gender specific spermatozoa using a multilayer density gradient

Interventions

Sperm Sorting

Selection of gender specific spermatozoa using a multilayer density gradient solution

Primary outcome measure

  • Rate of gender bearing spermatozoa after 4-layer density gradient [ Time Frame: 8 years ]
  • Rate of embryos of the desired gender in couples [ Time Frame: 8 years ]
  • Rate of offspring of the desired gender in couples [ Time Frame: 8 years ]

Central Contacts and Locations

Central contacts

Rodriq Stubbs, MS, NP

646-962-3276res2011@med.cornell.edu

Stephanie Cheung

646-962-8448stc3001@med.cornell.edu

Locations

Center for Reproductive Medicine- Weill Cornell Medicine

Recruiting

New York, New York, United States, 10021

Contacts

Rodriq Stubbs, MS, NP

646-962-3276res2011@med.conrell.edu

Stephanie Cheung

646-962-8448cts3001@med.conrell.edu

More Information

Sponsor

Weill Medical College of Cornell University

Last update posted

May 29, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-03. This information was provided to ClinicalTrials.gov by Weill Medical College of Cornell University on 2026-05-29.