Recruiting

Observational Study

Sponsor:

University of Alabama at Birmingham

Code:

NCT05507125

Conditions

Hidradenitis Suppurativa

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Mental health

Study Details

Brief summary:

The purpose of this protocol is to examine the cytokine profi le of pati ents with hidradeniti s suppurati va (HS) and idemechanisms responsible for post-transcripti onal regulati on of these genes. The primary objecti ve is to determinfollowing cytokines linked to hidradeniti s suppurati va are diff erenti ally expressed in hidradeniti s pati ents versus controlalso doing a sub-study to determine the eff ect of childhood trauma on HS. The parti cipati on in the sub-study is opti onal

Conditions

Hidradenitis Suppurativa

Study ID

NCT05507125

Start date

Oct 11, 2022

Status verified date

Aug, 2025

Completion date

Aug 31, 2028

Anticipated

Primary completion date

Aug 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Diagnosed with hidradenitis suppurativa
  • Not Pregnant

Exclusion Criteria:

  • Mild/general dermatological issues like moles, other cosmetic issues
  • Patients with hidradenitis suppurativa, psoriasis, roasacea, atopic dermatitis and other inflammatory skin disease
  • Pregnant

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Arms

Control

Participants without inflammatory skin disease

Patients with HS

Patients with HS

Interventions

Mental health

Early life exposure to abuse and development of hidradenitis suppurativa

Primary outcome measure

  • Inflammatory biomarkers [ Time Frame: 24 hours after application ]

Central Contacts and Locations

Central contacts

Nabiha Yusuf

2059347432nabihayusuf@uabmc.edu

Locations

Whitaker Clinic

Recruiting

Birmingham, Alabama, United States, 35294

Contacts

Nabiha Yusuf

2059347432nabihayusuf@uabmc.edu

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Aug 7, 2026

Last verified

Aug, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2026-08-07.