Recruiting

Carbohydrate Drink

Sponsor:

Hospital for Special Surgery, New York

Code:

NCT05520593

Conditions

Same-day Discharge

Length of Stay

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Complex Carbohydrate Drink

Study Details

Brief summary:

The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint arthroplasty.

Conditions

Same-day Discharge

Length of Stay

Study ID

NCT05520593

Start date

Nov 7, 2022

Status verified date

Feb, 2026

Completion date

Jan, 2027

Anticipated

Primary completion date

Jan, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Candidates for ambulatory total knee arthroplasty
  • Candidates for ambulatory total hip arthroplasty
  • Candidates for ambulatory revision knee arthroplasty (liner exchange only)
  • Candidates for ambulatory revision hip arthroplasty (liner exchange only)
  • Case scheduled before noon (12 pm)
  • Patient agrees to same-day discharge and has a responsible adult to spend the night on the day of discharge

Exclusion Criteria:

  • BMI less than 18.5 or greater than 37.0
  • Patients with diabetes, chronic kidney disease, clotting disorders, or neurological conditions preventing control of the affected limb.
  • Pregnant women
  • Patients scheduled as ambulatory due to insurance mandates
  • Patients with a history of active ischemia, significant valvular disease, significant arrhythmias, obstructive sleep apnea as per Hospital for Special Surgery guidelines, chronic opioid dependence (chronic daily opioid use for six or more months), and glomerular filtration rate < 60ml/min.

Study Design

Enrollment

312 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Complex Carbohydrate Drink Group

The patients will drink a 400ml drink that contains 50g of complex carbohydrates, 3 hours prior to the surgery. The drink will be given once at the preoperative holding area. Patients are not allowed to eat solid foods after 12am the morning of surgery and can only drink clear fluids up to 3 hours prior to the surgery.

no intervention: No-Complex Carbohydrate Drink Group

These patients will follow normal institutional preoperative fluid management guidelines, this consist of no solid foods after 12am the morning of surgery. Patients are allowed to drink clear liquids (water, clear fruit juices, coffee) from 12am the morning of surgery up to 3 hours prior to the surgery.

Interventions

Complex Carbohydrate Drink

Patients will drink a complex carbohydrate drink 3 hours before surgery. Drink to be given at the preoperative holding area.

Primary outcome measure

  • Length of hospital stay in hours [ Time Frame: From admission to discharge, up to 1 week ]

Central Contacts and Locations

Central contacts

Jose Rodriguez, MD

212-552-5829rodriguezjose@hss.edu

Ricardo Torres-Ramirez, BS

212-260-3763torresr@hss.edu

Locations

Hospital for Special Surgery

Recruiting

New York, New York, United States, 10021

Contacts

Ricardo Torres, BS

2122603763torresr@hss.edu

More Information

Sponsor

Hospital for Special Surgery, New York

Last update posted

Apr 13, 2026

Last verified

Feb, 2026

Keywords

  • Carbohydrate Drink
  • Perioperative Fluids
  • Same-day Discharge
  • Total Joint Arthroplasty
  • Nausea
  • Vomiting
  • Same-day total hip arthroplasty
  • Same-day total knee arthroplasty

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Hospital for Special Surgery, New York on 2026-04-13.