Recruiting

Observational Study

Sponsor:

Massachusetts General Hospital

Code:

NCT05524428

Conditions

Colo-rectal Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Implementation Science Strategy

Study Details

Brief summary:

The investigators will use a mixed methods study i.e. focus groups involving CHC staff as well as quantitative study which involves analyzing data that is available from the EHR and DRVS population management platform.

Conditions

Colo-rectal Cancer

Study ID

NCT05524428

Start date

Mar 24, 2023

Status verified date

Nov, 2025

Completion date

Dec, 2026

Anticipated

Primary completion date

Dec, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Staff members at partnering sites (see locations) who are administrative leaders, population health managers, data analysts, quality improvement staff, nurses, nurse managers, practice managers, medical assistants, and providers.
  • Staff members at partnering sites ages 18+.

Exclusion Criteria:

  • Staff members that are not involved in CRC screening practices at CHCs.

Study Design

Enrollment

2 participants

Anticipated

Allocation

Non randomized

Intervention Model

Sequential

Primary purpose

Screening

Interventions and Outcome Measures

Arms

other: Introduction of Implementation Strategies

The investigators will determine the best intervention and strategy (and thus implementers) based on high ranking barriers/facilitators identified in focus groups. A minimum of 2 implementation strategies will be developed and implemented at each level (patient, provider, system) at each site that considers (1) implementation strategy; (2) mechanism in which the strategy impacts the identified determinant (3) the determinant; (4) moderators that may influence the impact of the strategy; (5) the preconditions necessary for successful implementation; and (6) implementation outcomes affected. Each community health center (CHC) will serve as its own separate subject, and individual strategies will be tested using single case experimental design (SCED) at each CHC using component analysis to rapidly test and optimize our strategies. In SCED each subject serves as their own control, an intervention is systematically introduced and withdrawn, and the effects of the intervention are measured.

no intervention: Withdrawal of Implementation Strategies

In SCED each subject serves as their own control, an intervention is systematically introduced and withdrawn, and the effects of the intervention are measured.

Interventions

Implementation Science Strategy

The investigators will be conducting focus groups and identifying barriers and facilitators, and the investigators will be matching identified barriers and facilitators to implementation strategies at the patient, provider, and system level which the investigators will be testing using rapid-cycle methods.

Primary outcome measure

  • Primary Outcome 1: Acceptability of Implementation Strategies [ Time Frame: 4 months ]
  • Primary Outcome 2: Feasibility of Implementation Strategies [ Time Frame: 4 months ]
  • Primary Outcome 3: Appropriateness of Implementation Strategies [ Time Frame: 4 months ]

Central Contacts and Locations

Central contacts

Nathan Yoguez, MPH

nyoguez@mgh.harvard.edu

Locations

Codman Square Health Center

Recruiting

Boston, Massachusetts, United States, 02124

Brockton Neighborhood Health Center

Recruiting

Brockton, Massachusetts, United States, 02301

East Boston Neighborhood Health Center

Recruiting

East Boston, Massachusetts, United States, 02128

Duffy Health Center

Recruiting

Hyannis, Massachusetts, United States, 02601

More Information

Sponsor

Massachusetts General Hospital

Last update posted

Nov 14, 2025

Last verified

Nov, 2025

Keywords

  • colorectal cancer
  • cancer
  • screening
  • implementation science
  • health equity
  • cancer equity
  • healthcare access
  • minority health
  • early detection
  • public health
  • health justice
  • rapid testing

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Massachusetts General Hospital on 2025-11-14.