Recruiting

HIIGT vs. MICGT

Sponsor:

City University of New York

Code:

NCT05529498

Conditions

Multiple Sclerosis,Gait, Exercise

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Moderate paced continuous gait training

High Intensity Interval gait training

Study Details

Brief summary:

Over 90% of persons with MS (pwMS) complain of difficulty with walking. High intensity interval gait training (HIIGT), where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However its impact on pwMS is not known. Most gait training in MS is done continuously at a slower pace. The purpose of this study is to compare the effects of HIIGT to traditional Moderate Intensity Continuous Gait Training (MICGT) in pwMS.

Conditions

Multiple Sclerosis,Gait, Exercise

Study ID

NCT05529498

Start date

Sep 2, 2022

Status verified date

Sep, 2022

Completion date

Dec 31, 2023

Anticipated

Primary completion date

Dec 31, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria: Persons diagnosed with Multiple Sclerosis. Rationale:because we are studying effects of the intervention on participant with MS

  • The ability to walk for 6 minutes continuously with or without assistive device. Rationale:we are using the 6MWT as our primary outcome measure
  • The ability to read, understand and sign a consent form so that they are able to understand the study we are doing
  • Above the age of 18 because they have to be able to give consent for the study
  • English speaking as we do not have the resources for translation for the multiple sessions this study entails

Exclusion Criteria:Any cardiopulmonary, orthopedic, or non-MS neurologic disease as we are only examining the effects of MS and need to rule out the impact of other conditions

  • Report of a recent exacerbation. Rationale: the impact of the rationale can interfere with the impact of the independent variables

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Experimental

High intensity interval gait training

active comparator: Control

Moderate intesnity continuous gait training

Interventions

Moderate paced continuous gait training

walking continuously for 20 minutes at a moderate pace

High Intensity Interval gait training

20 minutes of interspersing 30 seconds of fast walking with 1 minute of rest

Primary outcome measure

  • 6 minute walk test [ Time Frame: 6 minutes ]

Central Contacts and Locations

Central contacts

Herbert Karpatkin, DSc

212-396-7115hkarpatk@hunter.cuny.edu

Jaya Rachwani, PhD

(212) 481-4321jr5856@hunter.local

Locations

Hunter College

Recruiting

New York, New York, United States, 11238

Contacts

Herbert Karpatkin, DSc

212-396-7115hkarpatk@hunter.cuny.edu

More Information

Sponsor

City University of New York

Last update posted

Sep 7, 2022

Last verified

Sep, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by City University of New York on 2022-09-07.