Recruiting

Scoliosis Assessment

Sponsor:

University of Alberta

Code:

NCT05538871

Conditions

Scoliosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Survey + Physical exam

Study Details

Brief summary:

Adults with scoliosis have not been the focus of much research in physical therapy despite their prevalence being very important. Adults with idiopathic scoliosis have a reported prevalence of about 2-11%. This includes adolescents with idiopathic scoliosis who have become adults but still have a scoliosis. They do not get much treatment as the adolescent treatment focuses on preventing worsening of the curvatures and the risk of progression is significantly reduced once a person reaches skeletal maturity. Still some patients experience self-image, function and pain issues which may be amenable to treatment using specific exercises as was recently shown. With ageing population a growing number of adults with de novo degenerative scoliosis is observed. This is a spinal misalignment due to spine degeneration. Adult degenerative scoliosis with pain is thought to affect about 24% of the ageing adults. This population has not been investigated very much.

Before planning conservative treatments for adults with scoliosis it would be important to describe what deficit these adults present that may be targeted by physical therapy. The objective of this study is to compare samples of patients with adults degenerative scoliosis, adult idiopathic scoliosis to matched healthy controls (for age, height and weight). Participants will complete questionnaires and a physical exam to identify which limitations they present that may be amenable to treatment with physical therapy. This information will assist planning trials to address the needs of these two neglected patient populations.

Conditions

Scoliosis

Study ID

NCT05538871

Start date

May 6, 2019

Status verified date

Jun, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion criteria for the idiopathic scoliosis group :

  • Diagnosis of idiopathic scoliosis
  • Age ⩾18 years old
  • Curve severity over 10°
  • Fluent in English.

Inclusion criteria for the degenerative scoliosis group :

  • Diagnosis of degenerative (De novo) scoliosis
  • Age ⩾45 years old
  • Curve severity over 10°
  • Fluent in English.

Exclusion criteria for the scoliosis groups :

  • History of spine surgery or
  • History of diseases affecting the torso or lower extremity function
  • Surgery or trauma
  • Secondary scoliosis
  • Unable to fill out the questionnaires or attend the physical examination,
  • Pregnant or gave birth between 0 and 2 years ago.

Inclusion criteria for healthy groups:

  • Age ⩾ 18 years
  • Matched for age/height/weight (+/-5 years; +/- 10 lbs; +/- 10cm) to a scoliosis participant
  • Fluent in English

Exclusion criteria for healthy groups:

  • Serious systemic pathology
  • Spine deformity
  • Spine surgery
  • Pregnant or gave birth between 0 and 2 years ago
  • Unable to fill out the questionnaires or attend the physical examination
  • Received treatments for the spine/the lower limbs within the last year

Study Design

Enrollment

108 participants

Anticipated

Interventions and Outcome Measures

Arms

Degenerative scoliosis

Diagnosis of degenerative (De novo) scoliosis,

Adult idiopathic scoliosis

Diagnosis of idiopathic scoliosis,

Degenerative scoliosis - matched controls

Population sample matched to the degenerative scoliosis group.

Idiopathic scoliosis - matched controls

Population sample matched to the idiopathic scoliosis group.

Interventions

Survey + Physical exam

Survey:

Demographic data Pain Oswestry disability index International Physical Activity Questionnaire Scoliosis Research Society (SRS-22r) Spinal appearance questionnaire Fear Avoidance and Beliefs Questionnaire Short Orebro musculoskeletal pain questionnaire Work Ability Index

Physical exam:

Repeated movements (MDT) Posture ROM Neuro Updated treatment based classification tests Pathoanatomical classification tests

Primary outcome measure

  • Socliosis Research Society 22-revised total score [ Time Frame: baseline ]

Central Contacts and Locations

Central contacts

Eric Parent, PT, PhD, Pr

+1 780-492-8889eparent@ualberta.ca

Locations

University of Alberta, Faculty of Rehabilitation Medicine, Dept. Physical Therapy

Recruiting

Edmonton, Alberta, Canada, T6G2G4

Contacts

Principal Investigator:

Eric C Parent, PhD, PT

More Information

Sponsor

University of Alberta

Last update posted

Jun 25, 2026

Last verified

Jun, 2026

Keywords

  • Scoliosis
  • Degenerative scoliosis
  • Idiopathic scoliosis
  • Adult scoliosis
  • ICF
  • Deficits

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alberta on 2026-06-25.