Recruiting

LGBTQ Youth Intervention

Sponsor:

Washington University School of Medicine

Code:

NCT05541406

Conditions

Depression

Anxiety

Post Traumatic Stress Disorder

Coping Behavior

Sexual Minority Stress

Eligibility Criteria

Sex: All

Age: 12 - 20

Healthy Volunteers: Accepted

Interventions

Proud & Empowered

Control Group

Study Details

Brief summary:

Efficacy of a Multi-level School Intervention for LGBTQ Youth

Conditions

Depression

Anxiety

Post Traumatic Stress Disorder

Coping Behavior

Sexual Minority Stress

Study ID

NCT05541406

Start date

Sep 14, 2022

Status verified date

Sep, 2026

Completion date

Apr 30, 2027

Anticipated

Primary completion date

Apr 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 12 - 20

Healthy Volunteers: Accepted

Inclusion Criteria:

  • LGBTQ student in one of 24 high schools

Exclusion Criteria:

  • Not meeting inclusion criteria

Study Design

Enrollment

228 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Intervention schools

Schools will be assigned to either intervention or control schools. Students in intervention schools will receive the intervention in semester 1.

active comparator: Control schools

Students in control schools will receive no intervention

Interventions

Proud & Empowered

Proud \& Empowered! is a school-based intervention to decrease sexual minority stress and improve coping among LGBTQ students. It is administered by school counselors and trained social workers.

Control Group

Schools in this condition will not receive the Proud \& Empowered intervention. Students in this condition will provide data spaced to align with the timing of the intervention delivered to schools in the other study arm.

Primary outcome measure

  • Sexual Minority Stress Inventory [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]
  • Beck Anxiety Inventory (BAI) [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]
  • PTSD Checklist for DSM-5 (PCL-5) [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]
  • Beck Depression Inventory [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]
  • Coping Strategies Inventory [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]
  • Adapted CSSRS Suicide Questions (Columbia Suicide Severity Rating Scale) [ Time Frame: Change between baseline and post-intervention/follow-up (12 weeks) ]

Central Contacts and Locations

Central contacts

Bethany N Lumsdaine, MPH

3103826003b.lumsdaine@wustl.edu

Locations

Washington University in St. Louis

Recruiting

St Louis, Missouri, United States, 63130

Contacts

Bethany Lumsdaine, MPH

b.lumsdaine@wustl.edu

More Information

Sponsor

Washington University School of Medicine

Last update posted

Sep 11, 2026

Last verified

Sep, 2026

Keywords

  • LGBTQ+ Youth
  • LGBT Youth
  • Queer Youth

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-27. This information was provided to ClinicalTrials.gov by Washington University School of Medicine on 2026-09-11. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.