Recruiting

Observational Study

Sponsor:

University of Alabama at Birmingham

Code:

NCT05556928

Conditions

Multiple Myeloma

Amyloidosis

Plasma Cell Leukemia

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The primary purpose of this protocol is to create a registry of older (≥50 years old) patients with Hematologic Malignancies. Our main objectives include: To understand the prevalence of frailty and geriatric impairments among patients aged ≥50y and above diagnosed with a hematologic malignancy at UAB and to gather information that would lend support for future research in this vulnerable population.

Conditions

Multiple Myeloma

Amyloidosis

Plasma Cell Leukemia

Study ID

NCT05556928

Start date

Jul 21, 2020

Status verified date

Dec, 2025

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Patients are ≥50 years of age.
  • Patients have a biopsy proven diagnosis of Hematologic Malignancy (Multiple Myeloma, AL Amyloidosis, Waldenstrom's Macrogloblunemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic syndromes, Myeloproliferative Neoplasm, Acute/Chronic Myeloid Leukemia, Acute/Chronic Lymphoid Leukemia).
  • Patients have appointments at UAB including if they are an inpatient or other clinic locations.

Exclusion Criteria:

  • Individuals who are <50 years old.
  • Patients who do not read and/or speak English will not be eligible for this study as many of the questionnaires are not validated in other languages. No exclusions will be made based on gender, ethnicity or race.

Study Design

Enrollment

5000 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Create the CARE-Heme Registry [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Landon Martin, BS

(205) 638-2120landoncmartin@uabmc.edu

Locations

Kirklin Clinic of UAB Hospital

Recruiting

Birmingham, Alabama, United States, 35294

Contacts

Smith Giri, Dr.

(205) 638-2120CAREheme@peds.uab.edu

More Information

Sponsor

University of Alabama at Birmingham

Last update posted

Dec 8, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alabama at Birmingham on 2025-12-08.