Recruiting

Gait Training

Sponsor:

Hunter College of City University of New York

Code:

NCT05560880

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

High Intensity Interval Gait training

Moderate Intensity Interval gait training

Study Details

Brief summary:

Over 90% of persons with MS (pwMS) complain of difficulty with walking. High intensity interval gait training (HIIGT), where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However its impact on pwMS is not known. Most gait training in MS is done continuously at a slower pace. The purpose of this study is to compare the effects of HIIGT to traditional Moderate Intensity Continuous Gait Training (MICGT) in pwMS.

Conditions

Multiple Sclerosis

Study ID

NCT05560880

Start date

Sep 1, 2022

Status verified date

Sep, 2022

Completion date

Dec 31, 2023

Anticipated

Primary completion date

Dec 31, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Persons diagnosed with Multiple Sclerosis.
  • The ability to walk for 6 minutes continuously with or without assistive device.
  • The ability to read, understand and sign a consent form so that they are able to understand the study we are doing
  • Above the age of 18

Exclusion Criteria:

  • Any cardiopulmonary, orthopedic, or non-MS neurologic disease as we are only examining the effects of MS and need to rule out the impact of other conditions
  • Report of a recent exacerbation. Rationale: the impact of the rationale can interfere with the impact of the independent variables

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: High Intensity Interval gait training

subjects will receive 3x/week high intensity interval training for 20 minutes over a 4 week period

active comparator: Moderate intensity continuous gait training

subjects will receive 3x/week moderate intensity continuous gait training for 20 minutes over a 4 week period

Interventions

High Intensity Interval Gait training

Subjects will walk as fast as they can for 30 seconds, followed by a 60 second seated recovery. They will be guarded by a physical therapist at all times.

Moderate Intensity Interval gait training

subjects will walk for 20 minutes at theri best comfortable pace

Primary outcome measure

  • Change in Six minute walk test time from before to after the intervention [ Time Frame: The test will be administered to all subjects one week before and one week after the intervention.The test will be administered to all subjects one week before and one week after the intervention. ]

Central Contacts and Locations

Central contacts

Herb Karpatkin, DSc

212-396-7115hkarpatk@hunter.cuny.edu

Locations

Hunter College

Recruiting

New York, New York, United States, 11238

Contacts

Herb Karpatkin, DSc

212-396-7115hkarpatk@hunter.cuny.edu

More Information

Sponsor

Hunter College of City University of New York

Last update posted

Oct 6, 2022

Last verified

Sep, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Hunter College of City University of New York on 2022-10-06.