Recruiting

Scrambler Therapy

Sponsor:

Johns Hopkins University

Code:

NCT05563038

Conditions

Post Stroke Pain

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Scrambler Therapy for Post Stroke Pain

Study Details

Brief summary:

The Investigators will enroll patients who have had a stroke and are experiencing post-stroke pain secondary to their infarct and disruption of the sensory system in a research study to compare the effectiveness of Scrambler Therapy to traditional pharmacologic therapies.

Conditions

Post Stroke Pain

Study ID

NCT05563038

Start date

May 15, 2023

Status verified date

Jan, 2026

Completion date

Dec, 2027

Anticipated

Primary completion date

Dec, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Men and women over the age of 18 with ischemic or hemorrhagic stroke seen on imaging and a positive finding for pain in the area(s) affected by their stroke location will be included.
  • The patients must be at least one month post-stroke but can otherwise enroll at any point.

Exclusion Criteria:

  • Patients with TIA
  • Patients with no evidence of stroke on MRI
  • Patients with implantable devices such as pacemakers, defibrillators, spinal cord stimulators
  • Patients with history of myocardial infarction in the past 6 months
  • Patients with uncontrolled epilepsy
  • Patients with symptomatic brain metastases

Study Design

Enrollment

100 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

active comparator: Scrambler Therapy

Using Scrambler Therapy for Post Stroke Pain all participants will either undergo either 5 or 10 treatments using Scrambler Therapy. The number of treatments will be decided by a randomization process.

Interventions

Scrambler Therapy for Post Stroke Pain

All participants will either undergo either 5 or 10 treatments using Scrambler Therapy. The number of treatments will be decided by a randomization process.

Primary outcome measure

  • Reduction in post stroke pain [ Time Frame: 6 months ]

Central Contacts and Locations

Central contacts

Dawn Merbach, MNP

4105508065dmerbac1@jhmi.edu

Erin Lawrence, MSN

4105508065ekilby1@jhmi.edu

Locations

Johns Hopkins Bayview Hospital

Recruiting

Baltimore, Maryland, United States, 21224

Contacts

Dawn Merbach, MSN,NP

410-550-6445dmerbac1@jhmi.edu

Erin Lawrence, MSN,NP

4105506445

More Information

Sponsor

Johns Hopkins University

Last update posted

Jan 26, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2026-01-26.