Recruiting

Observational Study

Sponsor:

UCLA

Code:

NCT05567133

Conditions

Sarcoidosis, Pulmonary

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.

Conditions

Sarcoidosis, Pulmonary

Study ID

NCT05567133

Start date

Jan 10, 2023

Status verified date

Jan, 2026

Completion date

Mar 30, 2030

Anticipated

Primary completion date

Mar 30, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. Adults with a diagnosis of sarcoidosis over the age of 18
2. Case definition: we will follow the 1999 statement on sarcoidosis published by the American Thoracic Society for diagnosis which includes tissue biopsy confirmation and exclusion of alternative diagnoses including beryllium sensitization/chronic beryllium disease, mycobacterial, viral, and/or fungal infection

Exclusion Criteria:

1. Inability to tolerate study procedures as determined by the investigator
2. Pregnant or breastfeeding
3. Concurrent medical diagnoses that would influence the expression of biomarkers will be considered an exclusion criterion. This includes diseases such as common variable immunodeficiency, HIV infection, or autoimmune diseases
4. Concurrent interstitial lung diseases such as hypersensitivity pneumonitis or idiopathic pulmonary fibrosis
5. Hematocrit (Packed Cell Volume) < 25%

Study Design

Enrollment

200 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Mean Change in Forced Vital Capacity in Liters [ Time Frame: Baseline and 24 months ]

Central Contacts and Locations

Central contacts

Laura Koth

4155144369laura.koth@ucsf.edu

Jessica Cardenas

jessica.cardenas@ucsf.edu

Locations

University of Maryland

Recruiting

Baltimore, Maryland, United States, 21201

Contacts

Wonder P Drake, MD

wdrake@som.umaryland.edu

UT Southwestern

Recruiting

Dallas, Texas, United States, 75390

Contacts

Fabiola Gianella

214-648-7875Fabiola.Gianella@UTsouthwestern.edu

More Information

Sponsor

University of California, San Francisco

Last update posted

Jan 8, 2026

Last verified

Jan, 2026

Keywords

  • sarcoid, lung, immune

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-11. This information was provided to ClinicalTrials.gov by University of California, San Francisco on 2026-01-08. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.