Recruiting

Observational Study

Sponsor:

University of Wisconsin, Madison

Code:

NCT05567744

Conditions

Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and Leukoencephalopathy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Interventions

Registry

Study Details

Brief summary:

This study is being done in order to create a registry (list) of people interested in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) research. It may be that you have a family member or other loved one with CADASIL, or that you may have CADASIL or are at risk. Participation means that your name will be added to a list of people who will be invited to participate in future research studies on CADASIL. Participants must be 18 years or older, and will remain on the registry until they request to be removed.

Conditions

Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and Leukoencephalopathy

Study ID

NCT05567744

Start date

Jun 3, 2022

Status verified date

Oct, 2025

Completion date

Oct, 2027

Anticipated

Primary completion date

Oct, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18 years of age or older
  • have a loved one or a family member with CADASIL, or are at-risk for CADASIL themselves

Exclusion Criteria:

  • Under 18 years of age

Study Design

Enrollment

2500 participants

Anticipated

Interventions and Outcome Measures

Arms

CADASIL Registry Participants

Have a loved one or family member with CADASIL, or anyone with or at risk for CADASIL

Interventions

Registry

Registry

Primary outcome measure

  • A Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) Registry [ Time Frame: Up to 20 years ]

Central Contacts and Locations

Central contacts

CADASIL Consortium

833-795-3016info@cadasil-consortium.org

Locations

University of Wisconsin

Recruiting

Madison, Wisconsin, United States, 53705

Contacts

CADASIL Consortium

833-795-3016info@cadasil-consortium.org

Principal Investigator:

Jane Paulsen, PhD

More Information

Sponsor

University of Wisconsin, Madison

Last update posted

Oct 16, 2025

Last verified

Oct, 2025

Keywords

  • CADASIL

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Wisconsin, Madison on 2025-10-16.