Recruiting

Observational Study

Sponsor:

Andrews Research & Education Foundation

Code:

NCT05568784

Conditions

Quadriceps Muscle Atrophy

Leg Injury

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

Interventions

Straight Leg Raise exercise

Study Details

Brief summary:

The goal of this study is to compare quadriceps muscle activation in patients recovering from lower extremity injury, such as an ACL tear. Specifically, the main objectives are as follows:

  • Determine the effects of ankle positioning on quad muscle activation during straight leg raise exercises performed while the patient is lying on his or her back
  • Determine if there is a difference between ankle positioning on quad muscle activation during straight leg raise exercises performed while the patient is lying on his or her back, comparing healthy versus post-operative participants

Conditions

Quadriceps Muscle Atrophy

Leg Injury

Study ID

NCT05568784

Start date

Apr 11, 2021

Status verified date

Feb, 2024

Completion date

Jul 3, 2024

Anticipated

Primary completion date

Apr 3, 2024

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Accepted

(All Participants)

Inclusion Criteria:

  • Males and females ages 18-55

Exclusion Criteria:

  • History of diagnosed cancer, neurological disorder, peripheral nerve injury affecting the lower limb or injury to the lower spine with radicular symptoms, which may affect quadriceps activation
  • History of musculoskeletal injury to the quadriceps that may affect ability to maintain muscle contractions without excessive fatigue or discomfort

(Healthy Participants)

Exclusion Criteria:

  • Injury to the knee or quadriceps muscle group within the past 12 months to the tested side
  • History of lower extremity orthopedic surgery in the past 12 months to the tested side

Study Design

Enrollment

100 participants

Anticipated

Interventions and Outcome Measures

Arms

Healthy Participants

Patients without pre-existing lower extremity injury that may inhibit response to testing

Participants with Knee Arthroscopy

Patients who have recently suffered knee injury that required arthroscopic surgery

Interventions

Straight Leg Raise exercise

Patient lying supine will lift leg to the height of the contralateral knee flexed to 90 degrees with the ankle positioned and tested in all three positions (dorsiflexion, neutral, and plantarflexion)

Primary outcome measure

  • Noraxon Ultium EMG [ Time Frame: Within first 28 days post-op (Arthroscopy patients); healthy patients tested at enrollment ]

Central Contacts and Locations

Central contacts

Chandler Bridges

8509168584chandler.bridges@andrewsref.org

Victora Williams

8509168487victoria.williams@andrewsref.org

Locations

Andrews Research and Education Foundation

Recruiting

Gulf Breeze, Florida, United States, 32561

Contacts

Jessi Truett

850-916-8570jessica.truett@andrewsref.org

Chandler Bridges

8509168584chandler.bridges@andrewsref.org

More Information

Sponsor

Andrews Research & Education Foundation

Last update posted

Feb 21, 2024

Last verified

Feb, 2024

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Andrews Research & Education Foundation on 2024-02-21.