Recruiting

Smoking Cessation

Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Code:

NCT05602753

Conditions

Smoking Cessation

Arthropathy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Lifestyle Counseling

Study Details

Brief summary:

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

Conditions

Smoking Cessation

Arthropathy

Study ID

NCT05602753

Start date

Feb 18, 2021

Status verified date

Nov, 2022

Completion date

Jan 31, 2025

Anticipated

Primary completion date

Jan 31, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults ages 18-85 who require a primary total hip or knee replacement
  • Any gender
  • Smokers and non-smokers
  • Osteoarthritis, rheumatoid arthritis, avascular necrosis

Exclusion Criteria:

  • Patients who require revision surgery
  • Previous fracture to affected area
  • Emergency surgery
  • Patients who do not understand, read or communicate in either French or English

Study Design

Enrollment

300 participants

Anticipated

Interventions and Outcome Measures

Arms

Smokers

All patients who participate in the study will complete the smoking history questionnaire and the carbon monoxide breath test. All patients with positive carbon monoxide breath test indicative of active nicotine exposure will be provided a structured smoking cessation program that includes information, counseling from their surgeon, or a trained health care professional and referral to a smoking cessation program.

Non-Smokers

Subjects who self-declared as non-smokers

Declared non-smokers with elevated Co2

subjects who self-declared as non-smokers but who tested positive for elevated Co2,

Interventions

Lifestyle Counseling

Referring to Stop smoking hotline, given pamphlets to encourage quitting smoking, pharmacy guidance, and possible referral to smoking cessation clinic.

Primary outcome measure

  • True incidence of smokers among patients undergoing joint replacement [ Time Frame: 15 minutes ]

Central Contacts and Locations

Central contacts

Adam Hart, MD

514-934-1934adam.hart@mgcill.ca

Karen Smith, CRA

514-934-1934karen.smith@muhc.mcgill.ca

Locations

Dr, Adam Hart

Recruiting

Montréal, Quebec, Canada, H3G 1A4

Contacts

Adam Hart, MD

514-934-1934adam.hart@mcgill.ca

Karen Smith

514-934-1934karen.smith@muhc.mcgill.ca

More Information

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Last update posted

Nov 4, 2022

Last verified

Nov, 2022

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by McGill University Health Centre/Research Institute of the McGill University Health Centre on 2022-11-04.