Recruiting

Observational Study

Sponsor:

The Cleveland Clinic

Code:

NCT05628948

Conditions

Cardiovascular Diseases

Metabolic Disease

Peripheral Artery Disease

Carotid Disease

Aneurysmal Disease

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpose of this initiative is to develop an enduring tool to allow for collaborative research between clinicians at Cleveland Clinic Main Campus and basic scientists at the Lerner Research Institute. This collaboration will allow resources to be available to clinical and basic researchers alike. This tool will enable research of vascular disease in the Vascular Lab and will leverage this valuable asset to the fullest extent to allow for interdepartmental collaboration.

Conditions

Cardiovascular Diseases

Metabolic Disease

Peripheral Artery Disease

Carotid Disease

Aneurysmal Disease

Study ID

NCT05628948

Start date

Nov 14, 2019

Status verified date

Dec, 2025

Completion date

Jun 30, 2031

Anticipated

Primary completion date

Dec 31, 2030

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

1. 18 years or older
2. Subjects capable of providing informed consent document
3. Subjects with diagnosed with or at risk for cardiovascular and metabolic diseases

Exclusion Criteria:

1. Known life expectancy of ≤ 6 months at the time of enrollment
2. Known current pregnancy
3. Severe Anemia (last documented hemoglobin < 7.0 g/dL)

Study Design

Enrollment

500 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • To collect blood, urine, and/or stool samples for biorepository [ Time Frame: 10 years ]

Central Contacts and Locations

Central contacts

Scott Cameron, MD, PhD

216-444-1680cameros3@ccf.org

Locations

Cleveland Clinic

Recruiting

Cleveland, Ohio, United States, 44195

Contacts

Scott Cameron, MD, PhD

216-444-1680cameros3@ccf.org

More Information

Sponsor

The Cleveland Clinic

Last update posted

Dec 19, 2025

Last verified

Dec, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by The Cleveland Clinic on 2025-12-19.