Recruiting

Observational Study

Sponsor:

Masonic Cancer Center, University of Minnesota

Code:

NCT05643014

Conditions

Healthy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Interventions

Sample collection

Study Details

Brief summary:

Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.

Conditions

Healthy

Study ID

NCT05643014

Start date

Feb 1, 2020

Status verified date

Mar, 2026

Completion date

Dec 31, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Firefighter (career or volunteer)
  • Over 18 years of age
  • Able to provide written voluntary consent

Exclusion Criteria:

  • Unwilling to provide a pre and post-exposure urine sample
  • Current cancer diagnosis
  • Tobacco use within the last 1 year (verified by urinary TNEs)

Study Design

Enrollment

60 participants

Anticipated

Interventions and Outcome Measures

Arms

Firefighters over 18 years old

This is a within subject, observational study of firefighters. This study will involve three sample collections including buccal cells and urine samples; one collection pre and two collections post-structural fire exposure.

Interventions

Sample collection

This study will involve three sample collections including buccal cells and urine samples

Primary outcome measure

  • Studying biomarker levels in firefighters pre and post fire call. [ Time Frame: 48 months ]

Central Contacts and Locations

Central contacts

Joni Jensen

612-624-5178jense010@umn.edu

Locations

Masonic Cancer Center

Recruiting

Minneapolis, Minnesota, United States, 55455

Contacts

Stephen S Hecht

612-624-7604hetcht002@umn.edu

Joni A Jensen

+1 612-624-7604jense010@umn.edu

More Information

Sponsor

Masonic Cancer Center, University of Minnesota

Last update posted

Mar 12, 2026

Last verified

Mar, 2026

Keywords

  • PAH
  • 1-HOP
  • PheT
  • SPMA

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Masonic Cancer Center, University of Minnesota on 2026-03-12.