Recruiting

Ultrasound Assessment

Sponsor:

Mayo Clinic

Code:

NCT05652023

Conditions

Bladder Dysfunction

Overactive Bladder

BPH With Urinary Obstruction

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Study Details

Brief summary:

The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.

Conditions

Bladder Dysfunction

Overactive Bladder

BPH With Urinary Obstruction

Study ID

NCT05652023

Start date

Apr 20, 2023

Status verified date

Mar, 2026

Completion date

Dec 20, 2028

Anticipated

Primary completion date

Dec 20, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Aim1:

Age >18 scheduled to undergo UDS for their clinical care for one of the included diagnoses.

-Aim2: Inclusions: Age >45 scheduled to undergo selective photovaporization of the prostate.

Exclusion Criteria:

  • Aim1:Obesity (BMI >35kg/m2), known neurologic disease impacting bladder function (e.g. spinal cord injury, multiple sclerosis, Parkinson's, prior cerebrovascular accident), previous pelvic radiation therapy, previous radical pelvic surgery (such as for uterine or colorectal cancer), prior bladder surgery (including prostate resection), and pregnant or breast-feeding women.
  • Aim2:Obesity (BMI >35kg/m2), known neurologic disease impacting bladder function (e.g. spinal cord injury, multiple sclerosis, Parkinson's, prior cerebrovascular accident), previous pelvic radiation therapy, previous radical pelvic surgery (such as colorectal cancer).

Study Design

Enrollment

2023 participants

Anticipated

Interventions and Outcome Measures

Primary outcome measure

  • Accuracy of quantitative ultrasound vibrometry for measuring detrusor pressure [ Time Frame: time Frame: Up to study completion, an average of 1 year ]

Central Contacts and Locations

Central contacts

Azra Alizad, MD

5075381727alizad.azra@mayo.edu

Kathryn (Katie) Barthels

5075385772Barthels.Kathryn@mayo.edu

Locations

Mayo Clinic

Recruiting

Rochester, Minnesota, United States, 55905

Contacts

Katie Barthels

507-538-5772barthels.kathryn@mayo.edu

Principal Investigator:

Azra Alizad, MD

More Information

Sponsor

Mayo Clinic

Last update posted

Mar 27, 2026

Last verified

Mar, 2026

Keywords

  • Detrusor Pressure
  • Bladder Compliance
  • Ultrasound
  • Ultrasound Vibrometery

Trial information was received from ClinicalTrials.gov and was last updated on 2026-10-10. This information was provided to ClinicalTrials.gov by Mayo Clinic on 2026-03-27. Recruitment status is synced daily from ClinicalTrials.gov and may not reflect the sponsor's current status. Confirm during your call.