Recruiting

Observational StudyMove With Air: Physiological Response Assessment

Sponsor:

McGill University

Code:

NCT05659550

Conditions

Chronic Obstructive Pulmonary Disease

Interstitial Lung Disease

Heart Failure

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

Honeywell HT-900 Turbo Force Air Circulator

Study Details

Brief summary:

A fan blowing cool air to the face has been shown to alleviate breathlessness in malignant and non-malignant disease at rest and during exercise, however the underlying physiological mechanisms remain unknown. This random order, three-condition design study will explore physiological mechanisms of breathlessness relief with fan-to-face therapy during constant-rate exercise in people with cardiorespiratory disease.

Conditions

Chronic Obstructive Pulmonary Disease

Interstitial Lung Disease

Heart Failure

Study ID

NCT05659550

Start date

Apr 1, 2023

Status verified date

Feb, 2024

Completion date

Dec 30, 2024

Anticipated

Primary completion date

Nov 30, 2024

Anticipated

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Inclusion Criteria:

have a physician diagnosis of cardiopulmonary disease (e.g., chronic obstructive pulmonary disease, interstitial lung disease, heart failure)
have a body mass index of >18.5 kg/m2 and <35 kg/m2
must be cleared by a physician to perform physical activity/exercise following the completion of the 'Medical Clearance Form for Cardiopulmonary Exercise Testing'.

Exclusion Criteria:

have changed their respiratory or cardiac medication dosage and/or frequency of administration in preceding two weeks
have had a disease exacerbation/hospitalization in preceding six weeks
have important contraindication(s) to exercise (e.g., significant musculoskeletal or neurological disease) or pulmonary function testing (e.g., eye, chest or stomach surgery, or any history of coughing up significant amounts of blood in the previous 3 months).

Study Design

Enrollment

21 participants

Anticipated

Allocation

Randomized

Intervention Model

Crossover

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Fan-to-face

The participants will complete a 4-minute constant work rate treadmill test with a basic, portable fan placed in front of the face. The fan will be placed at a location to target the second and third branches of the trigeminal nerve and will be placed a distance chosen by the participant so that the airflow speed is comfortable.

sham comparator: Fan-to-leg

no intervention: No fan

The participants will complete a 4-minute constant work rate treadmill test with no fan.

Interventions

Honeywell HT-900 Turbo Force Air Circulator

This is a basic, portable, household fan with a single cost of CDN$21.99.

Primary outcome measure

Borg modified 0-10 category ratio scale for breathlessness intensity [ Time Frame: End-exercise of the 4-minute constant rate treadmill test ]

Central Contacts and Locations

Central contacts

Rachelle I Aucoin, PhD Student

514-398-4184 rachelle.aucoin@mail.mcgill.ca

Dennis Jensen, PhD

514-398-4148 dennis.jensen@mcgill.ca

Locations

Centre of Innovative Medicine of the McGill University Health Centre

Recruiting

Montreal, Quebec, Canada, H4A 3J1

Contacts

Dennis Jensen, Ph.D.

514-398-4184 dennis.jensen@mcgill.ca

More Information

Sponsor

McGill University

Last update posted

Feb 15, 2024

Last verified

Feb, 2024

Keywords

Breathlessness
Dyspnea
Exercise
Fan-to-face therapy
Physiological Mechanisms
Constant work rate exercise

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by McGill University on 2024-02-15.