Recruiting

Biological Samples

Sponsor:

National Institute of Environmental Health Sciences (NIEHS)

Code:

NCT05666739

Conditions

Normal Physiology

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

Study Details

Brief summary:

Background:

Laboratory tests that use blood and urine can provide a great deal of information about human health and disease. To develop even better tests and to improve the ways samples are handled for testing researchers need to experiment with samples from healthy people.

Objective:

This natural history study will collect blood and urine from healthy people. The samples will build a repository that will be used for all kinds of research.

Eligibility:

Healthy people aged 18 years or older.

Design:

Participants will have 1 study visit. The visit will last up to 2 hours.

Participants will be screened. They will answer questions about their health history. They will list any medications they take. They will consent to donate samples for research and future use:

Blood: Up to 4.5 tablespoons of blood may be collected from a needle inserted into a vein.

Urine: Participants will be given a sterile container to provide a sample.

Some participants may be asked to provide other types of samples.

Some participants may be asked to provide new samples if their first ones are depleted.

Conditions

Normal Physiology

Study ID

NCT05666739

Start date

Jul 15, 2024

Status verified date

Jun 9, 2026

Completion date

Jul 19, 2032

Anticipated

Primary completion date

Jul 19, 2032

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Accepted

  • INCLUSION CRITERIA:

Inclusion Criteria for prospective biospecimen collection:

To be eligible to participate in this study, an individual must meet all the following criteria:

1. Stated willingness to comply with all study procedures and availability for the duration of the study.
2. Ability to provide informed consent.
3. Male or female, aged >=18
4. Able to travel to the NIEHS CRU for study visits

EXCLUSION CRITERIA:

Exclusion Criteria for prospective biospecimen collection:

An individual who meets any of the following criteria will be excluded from participation in this study:

1. Not willing to have samples stored for future use.
2. Any condition that, in the investigator s opinion, places the participant at undue risk for complications associated with required study procedures.

Study Design

Enrollment

2000 participants

Anticipated

Interventions and Outcome Measures

Arms

healthy controls

General public population, including females and males, who are over the age of 18, with a mixture of races and ethnicities representative of North Carolina

Primary outcome measure

  • To build a repository for approved investigators to access stored biological samples for the following: developing and testing specific laboratory assays, to maintain freezer and specimen handling quality control, to have blinded quality control... [ Time Frame: On-going ]

Central Contacts and Locations

Central contacts

NIEHS Join A Study Recruitment Group

(855) 696-4347myniehs@nih.gov

Lawrence S Kirschner, M.D.

(984) 287-3562lawrence.kirschner@nih.gov

Locations

NIEHS Clinical Research Unit (CRU)

Recruiting

Research Triangle Park, North Carolina, United States, 27709

Contacts

NIEHS Join A Study Recruitment Group

855-696-4347myniehs@nih.gov

More Information

Sponsor

National Institute of Environmental Health Sciences (NIEHS)

Last update posted

Jun 11, 2026

Last verified

Jun 9, 2026

Keywords

  • Blood
  • Urine
  • Assay Development
  • Natural History

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by National Institute of Environmental Health Sciences (NIEHS) on 2026-06-11.