Recruiting

Observational Study

Sponsor:

Icahn School of Medicine at Mount Sinai

Code:

NCT05675332

Conditions

Alcohol Drinking

Eligibility Criteria

Sex: All

Age: 21 - 35

Healthy Volunteers: Accepted

Interventions

Task-based behavioral intervention

Task-based behavioral intervention

Study Details

Brief summary:

The purpose of this study is to investigate the behavioral and neural correlates of stress exposure. Results from this study will enrich the understanding of how sociocultural, behavioral, and neural factors combine to influence alcohol use.

Conditions

Alcohol Drinking

Study ID

NCT05675332

Start date

Dec 9, 2022

Status verified date

Jun, 2026

Completion date

Jan 31, 2027

Anticipated

Primary completion date

Jan 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21 - 35

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Between 21 and 35 years of age (inclusive);
  • Fluent in English;
  • Right-handed

Exclusion Criteria:

  • Younger than 21 years of age;
  • Left-handed

Study Design

Enrollment

280 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

placebo comparator: no stress exposure

no threat stress

active comparator: stress exposure

exposure to stress threat

Interventions

Task-based behavioral intervention

Brief behavioral intervention is absent of stressors.

Task-based behavioral intervention

Brief behavioral intervention involves interacting with common everyday types of stress.

Primary outcome measure

  • Blood oxygen-level dependent (BOLD) signal [ Time Frame: Baseline ]
  • Resting-state functional connectivity in brain regions [ Time Frame: Baseline ]

Central Contacts and Locations

Central contacts

Shivani Doshi

212-241-6582shivani.doshi@mssm.edu

Locations

Icahn School of Medicine at Mount Sinai

Recruiting

New York, New York, United States, 10029

Principal Investigator:

Uraina Clark, PhD

More Information

Sponsor

Icahn School of Medicine at Mount Sinai

Last update posted

Jun 25, 2026

Last verified

Jun, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Icahn School of Medicine at Mount Sinai on 2026-06-25.