Recruiting

Heart Failure Program

Sponsor:

Cambridge Cardiac Care Centre

Code:

NCT05689086

Conditions

Heart Failure With Reduced Ejection Fraction

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Interventions

Virtual Heart Failure Optimization Program

Study Details

Brief summary:

The goal of this study is to test the impact of a virtual heart failure optimization program on uptake of guideline directed medical therapy, participation in cardiac rehabilitation \& impact on echocardiographic parameters.

Conditions

Heart Failure With Reduced Ejection Fraction

Study ID

NCT05689086

Start date

Jan 1, 2020

Status verified date

Jan, 2023

Completion date

Dec 31, 2023

Anticipated

Primary completion date

Dec 31, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • HFrEF (ejection fraction less than 40%) with New York Heart Association (NYHA) class II or III symptoms
  • Adults (>18 years of age), capable of providing informed consent, English-proficient and with access to a telephone

Exclusion Criteria:

  • Patients who are pregnant
  • Patients who who are incarcerated
  • Cardiac Transplant Patients
  • Patients with Left Ventricular Assist Devices

Study Design

Enrollment

400 participants

Anticipated

Interventions and Outcome Measures

Arms

Program Participants

Patients with HFrEF (LVEF<40%) \& NYHA class II-III who are referred to and consent to participate in the "Virtual Heart Failure Optimization Program"

Interventions

Virtual Heart Failure Optimization Program

Participants referred to the "Virtual Heart Failure Optimization Program" will be seen for initial consultation by a HF program nurse and cardiologist within 1 week. Patients will be offered the opportunity to participate in virtual cardiac rehabilitation.

Following this, patients will be assessed virtually every two weeks by a HF program nurse for addition and up-titration of medical therapy. All medication changes will be performed algorithmically and reviewed with the overseeing cardiologist. Following all medication changes, appropriate monitoring will be performed algorithmically as well.

All participants will be asked if they would like to participate in cardiac rehabilitation and an automatic referral will be sent by the overseeing cardiologist. Virtual cardiac rehabilitation will be conducted weekly with phone follow-up appointments with a program kinesiologist and virtual education programming.

Primary outcome measure

  • Change from baseline Doses of GDMT [ Time Frame: After completion of program (3 months) ]
  • Change from baseline Left Ventricular Ejection Fraction [ Time Frame: After completion of program (3 months) ]

Central Contacts and Locations

Central contacts

Locations

Cambridge Cardiac Rehab

Recruiting

Cambridge, Ontario, Canada, N1R 6V6

Contacts

Principal Investigator:

A. Pandey, MD

More Information

Sponsor

Cambridge Cardiac Care Centre

Last update posted

Jan 18, 2023

Last verified

Jan, 2023

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Cambridge Cardiac Care Centre on 2023-01-18.