Recruiting

Alcohol Biosensor

Sponsor:

University of Illinois at Urbana-Champaign

Code:

NCT05692830

Conditions

Alcohol Drinking

Alcohol Intoxication

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Interventions

Alcohol

Study Details

Brief summary:

The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing breathalyzer readings in real-world contexts. Also during this period, participants will attend three laboratory alcohol-administration sessions scheduled at one-week intervals, with alcohol dose and rate of consumption manipulated within and between participants, respectively. Laboratory visits will also double as ambulatory orientation, check-in, and close-out sessions.

Conditions

Alcohol Drinking

Alcohol Intoxication

Study ID

NCT05692830

Start date

Oct 22, 2022

Status verified date

Aug, 2025

Completion date

Sep 1, 2027

Anticipated

Primary completion date

Aug 1, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 21+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 21 years or older
  • drink alcohol at least 2x weekly

Exclusion Criteria:

  • psychological or medical conditions that might contraindicate alcohol-administration
  • history of adverse reaction to type and amount of beverage used in the study
  • currently seeking treatment for alcohol use disorder
  • does not drink alcohol regularly
  • taking drugs or medications for which alcohol consumption would be contraindicated
  • women who are pregnant or are attempting to become pregnant

Study Design

Enrollment

240 participants

Anticipated

Interventions and Outcome Measures

Interventions

Alcohol

Alcohol administered orally at multiple doses and consumption speeds to test transdermal device accuracy

Primary outcome measure

  • Transdermal estimates of alcohol consumption [ Time Frame: Across the 14 day period of the study ]
  • Transdermal estimates of drinking risk level [ Time Frame: Across the 14 day period of the study ]
  • Transdermal estimates of blood alcohol concentration [ Time Frame: Across the 14 day period of the study ]

Central Contacts and Locations

Central contacts

Catharine Fairbairn, PhD

217-300-5850uiucalcohollab@gmail.com

Locations

University of Illinois at Urbana-Champaign

Recruiting

Champaign, Illinois, United States, 61820

Contacts

Catharine E Fairbairn, Ph.D.

217 300 5850uiucalcohollab@gmail.com

More Information

Sponsor

University of Illinois at Urbana-Champaign

Last update posted

Aug 6, 2025

Last verified

Aug, 2025

Keywords

  • transdermal alcohol content
  • ambulatory
  • transdermal biosensor
  • machine learning algorithms
  • breath alcohol content

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Illinois at Urbana-Champaign on 2025-08-06.