Recruiting

Virtual Reality

Sponsor:

University of Alberta

Code:

NCT05695131

Conditions

Vocal Cord Dysfunction

Speech Disorders

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

GlenXRose Virtual Reality Speech Therapies

Study Details

Brief summary:

Factors related to successful rehabilitation are often directly related to adherence; for instance, dosage, frequency, and intensity can burden the patient regarding time and motivational factors. Furthermore, surrounding salience, patients may lose interest or find an intervention boring after a few sessions. It is well documented that nonadherence not only impacts rehabilitation for the patient but can also further prolong treatment, and increase hospital and clinician costs, in addition to a higher prevalence of future comorbidities. Therefore, strategies that improve patient adherence can significantly help optimize patient care and treatment outcomes.

One avenue to increase patient adherence is through the gamification of rehabilitation therapies using virtual reality (VR). Gamification of rehabilitation therapy can make mass practice required in rehabilitation therapies seemingly fun and more personally engaging for the patient. Additionally, the immersive experience achieved through VR can further promote salience and be customizable to individual patient requirements. As VR systems are now highly portable and relatively simple to utilize, they can provide an excellent opportunity to continue rehabilitation practice on the home front. Overall, the VR gamification of rehabilitation may increase adherence by shifting patients' perspectives of therapy as tedious, boring, or a hassle, to a fun and engaging game that ultimately helps their recovery processes.

The GlenXRose VR-delivered speech-language therapies (Cognitive Projections Lab, University of Alberta) have been developed and piloted in collaboration with the Glenrose Rehabilitation Hospital with the overall goal of increasing patient adherence, treatment outcomes, and satisfaction with vocal therapy. The proposed studies are to investigate the feasibility of implementing this technology in routine clinical care (specific to voice disorders), obtaining clinician feedback, examining associated financial costs, and continuing to examine the effect of the GlenXRose VR speech-language therapies on patient adherence and clinical outcomes, compared to traditional clinical care.

Conditions

Vocal Cord Dysfunction

Speech Disorders

Study ID

NCT05695131

Start date

Sep 20, 2023

Status verified date

May, 2026

Completion date

Jun 30, 2026

Anticipated

Primary completion date

Jun 30, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Adults receiving speech-language therapy at the Glenrose Rehabilitation Hospital (Edmonton, AB, Canada; Alberta Health Services)
  • Presence of a speech disorder
  • Proficiency in English
  • Able to provide signed informed consent to participate in the study

Exclusion Criteria:

  • Severe cognitive impairments and/or behavioural impairments
  • Communication disorders that impact comprehension of verbal commands and understanding of scale used in the study
  • Previous history of neurological or psychiatric disorder
  • Substance use disorders

Study Design

Enrollment

30 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Virtual Reality Delivered Therapy + Standard Clinical Care

The GlenXRose virtual reality therapies will be delivered to participants using a head-mounted device to allow vocal therapy and practice. Participants will also receive routine clinical care provided by speech-language pathologists.

no intervention: Standard Clinical Care

Participants will receive routine clinical care provided by speech-language pathologists.

Interventions

GlenXRose Virtual Reality Speech Therapies

Speech therapies for vocal cord disorders have been developed for virtual reality implementation. These include various games to interact with in a virtual environment while conducting rehabilitation therapy, in addition to educational visualizations

Primary outcome measure

  • Change in Frequency and Treatment Adherence Rates [ Time Frame: Up to 12 Weeks ]
  • Change in Generalization [ Time Frame: Up to 12 Weeks ]
  • Change in Compliance Rate [ Time Frame: Up to 12 Weeks ]
  • Change in Voice Handicap Index - 10 [ Time Frame: Up to 12 Weeks ]
  • Change in Acoustic Analysis of Voice [ Time Frame: Up to 12 Weeks ]

Central Contacts and Locations

Central contacts

Adriana Rios Rincon, PhD, R.OT

780.492.5150aros@ualberta.ca

Mathieu Figeys, PhD, RN

780.735.6296figeys@ualberta.ca

Locations

Glenrose Rehabilitation Hospital

Recruiting

Edmonton, Alberta, Canada, T5G 0B7

Contacts

More Information

Sponsor

University of Alberta

Last update posted

May 12, 2026

Last verified

May, 2026

Keywords

  • Vocal
  • Speech
  • Speech-Language Pathology
  • Virtual Reality
  • VR

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Alberta on 2026-05-12.