Recruiting

Lung Nodules

Sponsor:

Cedars-Sinai Medical Center

Code:

NCT05699213

Conditions

Lung Cancer

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Interventions

Lung MRI

Blood Draw

Study Details

Brief summary:

The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for lung cancer screening.

Conditions

Lung Cancer

Study ID

NCT05699213

Start date

Jun 27, 2023

Status verified date

Aug, 2023

Completion date

Aug 27, 2026

Anticipated

Primary completion date

Jun 27, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • Ability to read and understand informed consent
  • Male or female adults who are at high risk for lung cancer and are enrolled in the centralized lung cancer screening program: Based on USPSTF guidelines: Age 50-80 with 20 or greater pack-year smoking story who continue to smoke or quit within the past 15 years without sign or symptoms of lung cancer. Or based on National Comprehensive Cancer Network (NCCN) guidelines but do not meet the USPSTF guidelines, age 50-unlimited
  • Found to have one or more lung nodules that is 6mm or greater on screening LDCT

Exclusion Criteria:

  • Persons with an active diagnosis of cancer
  • Persons with active signs or symptoms of lung cancer
  • Persons with mechanically, magnetically, or electrically activated implants, such as cardiac pacemakers, neurostimulators, and infusion pumps.
  • Persons with ferromagnetic implants and ferromagnetic foreign bodies, such as intracranial aneurysm clips, shrapnel and intraocular metal chips as these could become dislodged.
  • Persons who are pregnant, nursing, are implanted with intrauterine devices (IUD's) that are not MR-compatible
  • Persons unable to tolerate MRI imaging secondary to an inability to lie supine or severe claustrophobia.
  • Persons who are non-compliant with visit instructions, including inability to lie still, hold breath or follow procedure instructions

Study Design

Enrollment

30 participants

Anticipated

Interventions and Outcome Measures

Interventions

Lung MRI

MRI of the lung

Blood Draw

Blood Draw

Primary outcome measure

  • Accrual and Retention Rate [ Time Frame: 3 years ]

Central Contacts and Locations

Central contacts

Weijia Chua, MD

310-423-1838weijia.chua@cshs.org

Locations

Cedars-Sinai Medical Center

Recruiting

Los Angeles, California, United States, 90048

More Information

Sponsor

Cedars-Sinai Medical Center

Last update posted

Aug 30, 2023

Last verified

Aug, 2023

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by Cedars-Sinai Medical Center on 2023-08-30.