Recruiting

Specialty Coffee

Sponsor:

University of Reading

Code:

NCT05709847

Conditions

Type 2 Diabetes

Eligibility Criteria

Sex: All

Age: 55 - 70

Healthy Volunteers: Not accepted

Interventions

Coffee

Study Details

Brief summary:

Coffee has been found to have beneficial effects on cognitive function and blood sugar control. Benefits include reduced risk of cognitive decline and improved performance on cognitive tests, as well as reduced risk of diabetes and improved blood sugar control in people with diabetes, a population that is at a higher risk of cognitive decline. These effects have been observed for both caffeinated and decaffeinated coffee, and have been associated with the polyphenol chlorogenic acid (CGA). This polyphenol has been found to be more bioavailable in certain coffees, known as "speciality coffee" as defined by the Specialty Coffee Association of America, depending on agriculture, roasting, and brewing method.

This current project will bring together these previous findings to explore the effects of specialty coffee on cognitive function and glycaemic control in people with type 2 diabetes through a randomized control trial with two groups: a high CGA specialty coffee group and a conventional coffee control group. Participants will be quasi-randomly assigned to one of these two groups following the completion of a 4-week run-in period during which participants will consume conventional coffee only. The length of the experimental arms is 8 weeks, therefore the total length of the study is 12 weeks. At the beginning and the end of each experimental arm participants will undertake a cognitive assessment online using the Gorilla platform, and a series of questionnaires relating to health and mood measures (details in procedure). Cognitive function will also be assessed at the beginning of the 4-week run-in period.

Conditions

Type 2 Diabetes

Study ID

NCT05709847

Start date

Jan 1, 2023

Status verified date

Jan, 2023

Completion date

Jan 1, 2025

Anticipated

Primary completion date

Jan 1, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 55 - 70

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 55-70 years
  • Formal diagnosis of Type 2 Diabetes for 3 years or more
  • Current coffee drinkers, 4 or fewer cups daily (a cup is 8 oz)

Exclusion Criteria:

  • Insulin-dependent
  • Consuming on average more than 4 cups of coffee daily
  • Regularly consuming specialty coffee (participants will be provided with a list of these coffees)

Study Design

Enrollment

70 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Basic Science

Interventions and Outcome Measures

Arms

active comparator: Conventional coffee

Participants will be provided with a conventional, low CGA coffee to brew and consume which contains less CGA than the experimental arm.

experimental: CGA-rich coffee (Speciality coffee)

Participants will be provided with a single origin, CGA-rich specialty coffee as graded by the Specialty Coffee Association of America's Q-grading system to brew and consume

Interventions

Coffee

24 ounces of coffee will be consumed daily

Primary outcome measure

  • Verbal memory [ Time Frame: 8 weeks ]
  • Verbal memory [ Time Frame: 0 weeks ]
  • Verbal memory [ Time Frame: -4 weeks ]

Central Contacts and Locations

Central contacts

Locations

Kaiser Permanente

Recruiting

Berkeley, California, United States, 94710

Contacts

More Information

Sponsor

University of Reading

Last update posted

Feb 2, 2023

Last verified

Jan, 2023

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Reading on 2023-02-02.