Recruiting

Smoking Cessation

Sponsor:

University of Vermont Medical Center

Code:

NCT05738408

Conditions

Smoking Cessation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Financial Incentives (FI) and Nicotine Replacement Therapy (NRT)

Study Details

Brief summary:

The investigators are proposing to examine new strategies for helping patients hospitalized for an acute coronary event adhere to recommendations to quit smoking. The investigators are interested to see whether offering financial incentives for smoking cessation, combined with medications to ameliorate withdrawal, can significantly reduce smoking in a population for which continued smoking has disproportionately negative health effects. The proposed trial can provide significant knowledge for promoting adherence to smoking cessation guidelines in patients with cardiac disease

Conditions

Smoking Cessation

Study ID

NCT05738408

Start date

Aug 12, 2022

Status verified date

Jan, 2025

Completion date

Dec, 2025

Anticipated

Primary completion date

Jul, 2025

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

Patients will be recruited if they:

1. Hospitalization for an acute coronary event which includes myocardial infarction or coronary revascularization (percutaneous intervention or coronary artery bypass)
2. live within 30 miles of UVMMC and are >18 years of age
3. Current cigarette smoker (defined as reporting any use of cigarettes in the week before admission and >5 cigarette/day on average over the past 3 months)

Exclusion Criteria:

Patients will be excluded if they have:

1. severe dementia/Alzheimer's disease
2. an active malignancy, excluding non-melanoma skin cancer or low-grade prostate cancer under active surveillance
3. exercise limiting vascular or neuromuscular disease
4. Non-English Speaking
5. No reliable smart-phone
6. Current, regular use of smokeless tobacco or other form of non-combusted tobacco

Study Design

Enrollment

50 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

no intervention: Control: Usual Care

will receive standard treatment which entails referral to Vermont Quit Network. This network offers a wide range of free cessation services, including NRT and web-based modules on preparing to quit and developing a plan

experimental: Intervention: Financial incentives and nicotine replacement therapy intervention

an intervention where patients are assigned to financial incentives and NRT of their choice; use of CO monitor to assess abstinence

Interventions

Financial Incentives (FI) and Nicotine Replacement Therapy (NRT)

: In the intervention condition, patients will receive both NRT plus a 12-week program of monetary incentives for verified smoking abstinence that will be implemented by our clinic staff

Primary outcome measure

  • Biochemical verification of smoking status [ Time Frame: 3 months ]

Central Contacts and Locations

Central contacts

Sherrie Khadanga, MD

802-847-2700sherrie.khadanga@uvmhealth.org

Diann Gaalema, PhD

diann.gaalema@med.uvm.edu

Locations

University of Vermont Medical Center

Recruiting

Burlington, Vermont, United States, 05405

Contacts

Sherrie Khadanga

802-847-2700sherrie.khadanga@uvmhealth.org

More Information

Sponsor

University of Vermont Medical Center

Last update posted

Jan 20, 2025

Last verified

Jan, 2025

Keywords

  • smoking cessation
  • secondary prevention

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Vermont Medical Center on 2025-01-20.