Recruiting

MAYA App

Sponsor:

Weill Medical College of Cornell University

Code:

NCT05754151

Conditions

Anxiety Disorders and Symptoms

Depressive Symptoms

Depression

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Interventions

MAYA Mobile Application

Study Details

Brief summary:

This study aims to assess a mobile app called MAYA for use in middle-aged and older adults with anxiety or mood disorders. The MAYA app is designed to teach coping skills for anxiety and depression that are drawn from cognitive behavioral therapy. Participants will be asked to use the app for at least two days a week, 20 minutes on each day, for six weeks. Participants will have weekly check-ins as well as longer assessments at the beginning of the study, week 3, week 6 (end of treatment), and week 12 (follow up). During assessments, participants will answer brief questionnaires designed to assess their symptoms and impressions of the app. The main hypotheses of the study are that participants will complete most of the assigned sessions and that they will rate their impressions of the app highly. The secondary hypotheses are that symptoms of depression and anxiety will decrease with use of the MAYA app.

Conditions

Anxiety Disorders and Symptoms

Depressive Symptoms

Depression

Study ID

NCT05754151

Start date

Jun 16, 2023

Status verified date

May, 2026

Completion date

Jun, 2027

Anticipated

Primary completion date

Jun, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 40+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Age 40 or older
  • Primary diagnosis of an anxiety or depressive disorder as determined by a clinical severity rating score of 4 or greater on the Anxiety Disorders Interview Schedule (ADIS).
  • Mini Mental Status Exam (MMSE) no more than 1 SD below the mean score for patient's age and education. If the remote version of the MMSE is used (e.g. during an evaluation on Zoom), the remote MMSE score will be converted to a standard MMSE score.
  • Access to an Apple iPhone, iPad, or Android device.

Exclusion Criteria:

  • Lifetime diagnosis of a bipolar or psychotic disorder.
  • Currently in cognitive behavior therapy.
  • Change in dose of a psychiatric medication in the past 12 weeks.
  • Initiation of psychotherapy in the past 12 weeks.
  • Intent or plan to attempt suicide.

Study Design

Enrollment

60 participants

Anticipated

Intervention Model

Single group

Primary purpose

Supportive Care

Interventions and Outcome Measures

Arms

experimental: MAYA Mobile App

Participants receive treatment with the MAYA application for 6 weeks

Interventions

MAYA Mobile Application

The mobile cognitive behavioral therapy (CBT) application, MAYA, teaches cognitive behavioral therapy (CBT) techniques including emotion monitoring, cognitive restructuring, mindfulness, exposure and psychoeducation (i.e. information about anxiety and depression). The application includes an interactive dashboard to provide the user with statistics for tracking progress toward their goals. Although the MAYA application is new, its content and structure are similar to how CBT- a well-established and widely used psychosocial intervention - is commonly delivered in the more traditional setting of a psychotherapist's office.

Primary outcome measure

  • Acceptability of the MAYA application as measured by mean uMARS scores at Baseline [ Time Frame: Week 1 (Baseline) ]
  • Acceptability of the MAYA application as measured by mean uMARS scores at Midpoint [ Time Frame: Week 3 (Midpoint) ]
  • Acceptability of the MAYA application as measured by mean uMARS scores at Endpoint [ Time Frame: Week 6 (Endpoint) ]
  • Feasibility of the MAYA application as measured by total number of sessions completed in the MAYA application at Endpoint [ Time Frame: Week 6 (Endpoint) ]
  • Feasibility of the MAYA application as measured by total number of sessions completed in the MAYA application at Follow Up [ Time Frame: Week 12 (Follow Up) ]

Central Contacts and Locations

Central contacts

Maddy Schier

(646) 289-5271mas4019@med.cornell.edu

Zareen Mir

(646)-289-5271zam4005@med.cornell.edu

Locations

Weill Cornell Medicine

Recruiting

New York, New York, United States, 10065

Contacts

Jennifer Bress, Ph.D

914.997.8683jeb2061@med.cornell.edu

Maddy Schier

(646) 289-5271mas4019@med.cornell.edu

Principal Investigator:

Jennifer Bress, Ph.D

More Information

Sponsor

Weill Medical College of Cornell University

Last update posted

May 22, 2026

Last verified

May, 2026

Keywords

  • Anxiety
  • CBT
  • Mobile Application
  • Cognitive Behavioral Therapy
  • Depression
  • Older Adults
  • Adults

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Weill Medical College of Cornell University on 2026-05-22.