Recruiting

Observational Study

Sponsor:

University of Southern California

Code:

NCT05786664

Conditions

Anatomic Stage I Breast Cancer AJCC v8

Anatomic Stage II Breast Cancer AJCC v8

Anatomic Stage III Breast Cancer AJCC v8

Invasive Breast Carcinoma

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Electronic Health Record Review

Quality-of-Life Assessment

Survey Administration

Study Details

Brief summary:

This study collects blood samples as well as clinical and self-report data from stage I-III breast cancer survivors to create a biorepository for future use. The creation of this biorepository will allow for future research into links between individual, molecular, and genomic signatures and cancer outcomes.

Conditions

Anatomic Stage I Breast Cancer AJCC v8

Anatomic Stage II Breast Cancer AJCC v8

Anatomic Stage III Breast Cancer AJCC v8

Invasive Breast Carcinoma

Study ID

NCT05786664

Start date

Apr 11, 2022

Status verified date

May, 2026

Completion date

Apr 11, 2028

Anticipated

Primary completion date

Apr 11, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Women of all racial and ethnic groups 18 years of age or older
  • Women with a diagnosis of invasive breast cancer (stages I-III) within the past 7 years
  • Women who have completed active treatment for breast cancer (surgery, chemotherapy, HER2-directed therapy and radiation)
  • Prior participation on clinical trials is allowed

Exclusion Criteria:

  • Current receipt of interventional clinical trial participation
  • Stage IV (metastatic) cancer
  • Prior history of recurrence (except recurrence following ductal carcinoma in situ)
  • Inability to give informed consent
  • Unable to speak English, Spanish, Chinese, or Korean

Study Design

Enrollment

1300 participants

Anticipated

Interventions and Outcome Measures

Arms

Observational (survey, biospecimen collection, record review)

Patients complete surveys, undergo collection of blood samples, and review of medical records on study.

Interventions

Biospecimen Collection

Undergo collection of blood samples

Electronic Health Record Review

Review of records

Quality-of-Life Assessment

Complete quality-of-life questionnaires

Survey Administration

Complete surveys

Primary outcome measure

  • Biorepository [ Time Frame: 5 years ]

Central Contacts and Locations

Central contacts

Audrey Saghian, MPH

323-865-6086amsaghia@usc.edu

Locations

USC / Norris Comprehensive Cancer Center

Recruiting

Los Angeles, California, United States, 90033

Contacts

Audrey Saghian, MPH

323-865-6086Amsaghia@usc.edu

Principal Investigator:

Bodour Salhia, PhD

More Information

Sponsor

University of Southern California

Last update posted

May 28, 2026

Last verified

May, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Southern California on 2026-05-28.