Recruiting

Personalized Feedback

Sponsor:

University of Washington

Code:

NCT05787015

Conditions

COVID-19

Vaccine Hesitancy

Eligibility Criteria

Sex: All

Age: 18 - 24

Healthy Volunteers: Accepted

Interventions

Vaccine Norms Feedback

Alcohol Norms Feedback

Study Details

Brief summary:

Rationale: The highest rates of coronavirus disease (i.e., COVID-19) vaccine hesitancy in the US are among young adults (YAs) aged 18-25. Our preliminary studies show that social norms - perceptions of peers' vaccination attitudes/behaviors - are most strongly related to YAs' vaccine intentions/uptake. Most YAs underestimate the perceived importance of vaccination and their peers' intentions to be vaccinated. The proposed research will develop and test an intervention to correct misperceived norms for vaccination hesitancy and uptake.

Methodology: Rapid prototyping with 20 unvaccinated YAs will help refine the content and design of the online intervention. Then, a diverse national sample (N=600) of unvaccinated YAs will be randomized to treatment or an attention-matched control. The treatment condition will receive personalized normative feedback (PNF) designed to correct normative misperceptions for vaccine hesitancy and uptake.

Normative feedback will be derived from the US Census Bureau's Household Pulse Survey. Follow-up surveys will be administered at 1, 2, 3, and 6 months to assess key outcomes including vaccine uptake, intentions, and reasons for vaccine hesitancy.

Aims and Data Analysis:

  • Aim 1: Develop and refine a PNF intervention for vaccine hesitancy/uptake with user feedback from YAs. Rapid analysis of qualitative data will involve looking for themes in responses. Changes will be made iteratively to refine intervention content, design, and delivery.
  • Aim 2: Evaluate intervention efficacy for increasing vaccine uptake and reducing time to first vaccine dose, relative to control, over the following year.
  • Aim 3: Examine mediators (changes in perceived norms) and moderators (intellectual humility, identification with other people and young adults) of intervention efficacy. A longitudinal moderated mediation model will be examined.

Impact: Findings will clarify the causal role of psychological determinants of vaccine hesitancy (social norms, intellectual humility, group identification). If preliminary intervention efficacy is supported, this intervention could be a low-cost, and easily disseminated strategy to promote YAs' vaccine uptake and contribute to public health efforts to address the COVID-19 pandemic.

Conditions

COVID-19

Vaccine Hesitancy

Study ID

NCT05787015

Start date

Oct 6, 2022

Status verified date

Mar, 2023

Completion date

Dec, 2024

Anticipated

Primary completion date

Oct, 2023

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 24

Healthy Volunteers: Accepted

Inclusion Criteria:

  • 18-24 years old (at screening)
  • Reside in the United States.
  • Have not received a COVID-19 vaccine (at screening)
  • Pass attention checks.

Exclusion Criteria:

  • Not meeting inclusion criteria.
  • Not fluent in English.
  • Not providing consent.
  • Unwilling to participate.

Study Design

Enrollment

600 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Prevention

Interventions and Outcome Measures

Arms

experimental: Vaccine Norms Feedback

The participants in the treatment condition will receive personalized normative feedback (PNF) that entails correcting normative misperceptions for US young adults' vaccine uptake rates and prevalence of vaccine hesitancies (e.g., fear of side effects). Participants will be shown discrepancies between their perceived estimate of young adults' vaccination rates and actual national estimates derived from the US Census Bureau's Household Pulse Survey to highlight, in most cases, that they underestimated the vaccination norms.

active comparator: Alcohol Norms Feedback

Participants randomized to control will complete all measures at the same time as participants in the treatment condition, but will not receive any normative information regarding vaccines. Instead, to match for attention and provide potential benefit, those in the control condition will receive a standard dynamic norms feedback pertaining to alcohol use norms and behaviors.

Interventions

Vaccine Norms Feedback

Personalized normative feedback pertaining to normative misperceptions about vaccination rates and hesitant attitudes.

Alcohol Norms Feedback

Personalized normative feedback pertaining to normative misperceptions about alcohol use.

Primary outcome measure

  • COVID-19 vaccine uptake [ Time Frame: Through study completion, an average of 6 months ]
  • COVID-19 vaccine attitudes [ Time Frame: Through study completion, an average of 6 months ]

Central Contacts and Locations

Central contacts

Scott Graupensperger, PhD

206-543-0080graups@uw.edu

Locations

University of Washington

Recruiting

Seattle, Washington, United States, 98195

Contacts

Scott Graupensperger, PhD

206-543-0080graups@uw.edu

Jack Hilovsky

206-543-0080jhilov@uw.edu

More Information

Sponsor

University of Washington

Last update posted

Mar 28, 2023

Last verified

Mar, 2023

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by University of Washington on 2023-03-28.