Recruiting
Phase 2

Carboplatin

Sponsor:

SWOG Cancer Research Network

Code:

NCT05806515

Conditions

Prostate Adenocarcinoma

Stage IIIB Prostate Cancer AJCC v8

Stage IIIC Prostate Cancer AJCC v8

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Carboplatin

Chest Radiography

Computed Tomography

Magnetic Resonance Imaging

Study Details

Brief summary:

This phase II trial tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. Giving carboplatin before surgery may shrink tumors in patients with high-risk prostate cancer with BRCA1 and BRCA2 gene mutations.

Conditions

Prostate Adenocarcinoma

Stage IIIB Prostate Cancer AJCC v8

Stage IIIC Prostate Cancer AJCC v8

Study ID

NCT05806515

Start date

Mar 1, 2024

Status verified date

Jan, 2026

Completion date

Jun, 2031

Anticipated

Primary completion date

Jul, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Participant must have histologic diagnosis of prostate adenocarcinoma
  • Participant must have high or very high-risk disease defined by at least one of the following:

  • cT3a - cT4x
  • Grade group 4 or 5 (Gleason sum 8-10)
  • PSA > 20 ng/mL prior to registration
  • Participant must have documented evidence of germline mutation (pathogenic/likely pathogenic variant) in BRCA2 or BRCA1 through testing in a Clinical Laboratory Improvement Act (CLIA)-certified lab

  • NOTE: Local lab report is sufficient for eligibility
  • Participant may have initiated gonadotrophin releasing hormone (gnRH) agonist, gnRH antagonist, oral anti-androgen (e.g. bicalutamide, nilutamide, flutamide), or other agent intended to treat prostate cancer prior to registration. The effectiveness of the current depot of such treatment must not extend beyond 1 month after study registration. Agents listed above cannot be started after participant registration
  • Participant must be >= 18 years old
  • Participant must have Zubrod performance status of 0-2
  • Participant must have a complete medical history and physical exam within 28 days prior to registration
  • Absolute neutrophil count >= 1.5 x 10\^3/uL (within 28 days prior to registration)
  • Platelets >= 100 x 10\^3/uL (within 28 days prior to registration)
  • Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 3 x institutional upper limit of normal (ULN) (within 28 days prior to registration)
  • Participant must have a serum creatinine =< the institutional upper limit of normal (IULN) OR measured OR calculated creatinine clearance >= 50 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration
  • Participant must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification within 28 days prior to registration. To be eligible for this trial, participants must be class 2B or better
  • Participant with known human immunodeficiency virus (HIV)-infection must be receiving anti-retroviral therapy and have an undetectable viral load test within 6 months prior to registration
  • Participant with history of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load on suppressive therapy within in 28 days prior to registration
  • Participant with a history of hepatitis C virus (HCV) infection must have been treated and cured. For participants with HCV infection who are currently on treatment must have an undetectable HCV viral load within in 28 days prior to registration
  • Participants who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including vasectomy with testing showing no sperm in the semen
  • Prior to registration, participant must have had a urologic consult and be deemed a surgical candidate with known sites of disease deemed by the urologist to be potentially resectable
  • Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the Southwest Oncology Group (SWOG) Specimen Tracking System
  • NOTE: As a part of the OPEN registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

  • Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines
  • For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations
  • As part of the registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

Exclusion Criteria:

  • Participant must not have evidence of distant metastatic disease by conventional imaging within 90 days prior to registration

  • NOTE: cN1 detected only by PSMA-PET is permitted if urologist deems sites of disease to be potentially completely resectable
  • Participant must not have received prior radiation therapy (RT) to the pelvic region
  • Participant must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of protocol treatment

Study Design

Enrollment

44 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Treatment (carboplatin)

Patients receive carboplatin IV on study. Patients then undergo surgery on study. Patients who experience PSA progression after surgery undergo CT or MRI of the abdomen and pelvis, CT of the chest or chest X-ray, or PSMA-PET throughout the trial. Patients also undergo collection of blood samples throughout the trial.

Interventions

Biospecimen Collection

Undergo collection of blood samples

Carboplatin

Given IV

Chest Radiography

Undergo chest X-ray

Computed Tomography

Undergo CT

Magnetic Resonance Imaging

Undergo MRI

PSMA PET Scan

Undergo PSMA PET

Surgical Procedure

Undergo surgery

Primary outcome measure

  • Pathologic complete response after neoadjuvant carboplatin [ Time Frame: Up to 5 years ]

Central Contacts and Locations

Locations

Anchorage Associates in Radiation Medicine

Recruiting

Anchorage, Alaska, United States, 98508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Anchorage Radiation Therapy Center

Recruiting

Anchorage, Alaska, United States, 99504

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Alaska Breast Care and Surgery LLC

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Alaska Oncology and Hematology LLC

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Alaska Women's Cancer Care

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Anchorage Oncology Centre

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Katmai Oncology Group

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Providence Alaska Medical Center

Recruiting

Anchorage, Alaska, United States, 99508

Contacts

Site Public Contact

907-212-6871AKPAMC.OncologyResearchSupport@providence.org

Principal Investigator:

Charles W. Drescher

Cancer Center at Saint Joseph's

Recruiting

Phoenix, Arizona, United States, 85004

Contacts

Site Public Contact

602-406-0777Research-cancerinstitute@dignityhealth.org

Principal Investigator:

Shahzad Siddique

Mission Hope Medical Oncology - Arroyo Grande

Recruiting

Arroyo Grande, California, United States, 93420

Contacts

Site Public Contact

805-219-4673ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Recruiting

Burbank, California, United States, 91505

Contacts

Site Public Contact

818-847-4793Najee.Boucher@providence.org

Principal Investigator:

Charles W. Drescher

Mercy Cancer Center �� Carmichael

Recruiting

Carmichael, California, United States, 95608

Contacts

Site Public Contact

protocols@swog.org

Principal Investigator:

Shahzad Siddique

Mercy San Juan Medical Center

Recruiting

Carmichael, California, United States, 95608

Contacts

Site Public Contact

916-556-3301OncologyResearch@DignityHealth.org

Principal Investigator:

Shahzad Siddique

City of Hope Comprehensive Cancer Center

Recruiting

Duarte, California, United States, 91010

Contacts

Site Public Contact

800-826-4673becomingapatient@coh.org

Principal Investigator:

Wesley Yip

Mercy Cancer Center - Elk Grove

Recruiting

Elk Grove, California, United States, 95758

Contacts

Site Public Contact

916-556-3301OncologyResearch@DignityHealth.org

Principal Investigator:

Shahzad Siddique

City of Hope at Irvine Lennar

Recruiting

Irvine, California, United States, 92618

Contacts

Site Public Contact

877-467-3411

Principal Investigator:

Wesley Yip

Providence Queen of The Valley

Recruiting

Napa, California, United States, 94558

Contacts

Site Public Contact

707-521-3830

Principal Investigator:

Charles W. Drescher

Mercy Cancer Center - Rocklin

Recruiting

Rocklin, California, United States, 95765

Contacts

Site Public Contact

916-556-3301OncologyResearch@DignityHealth.org

Principal Investigator:

Shahzad Siddique

Mercy Cancer Center - Sacramento

Recruiting

Sacramento, California, United States, 95816

Contacts

Site Public Contact

916-556-3301OncologyResearch@DignityHealth.org

Principal Investigator:

Shahzad Siddique

Pacific Central Coast Health Center-San Luis Obispo

Recruiting

San Luis Obispo, California, United States, 93401

Contacts

Site Public Contact

805-219-4673ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Mission Hope Medical Oncology - Santa Maria

Recruiting

Santa Maria, California, United States, 93444

Contacts

Site Public Contact

805-219-4673ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Providence Medical Foundation - Santa Rosa

Recruiting

Santa Rosa, California, United States, 95403

Contacts

Site Public Contact

707-521-3830

Principal Investigator:

Charles W. Drescher

Providence Santa Rosa Memorial Hospital

Recruiting

Santa Rosa, California, United States, 95405

Contacts

Site Public Contact

707-521-3830

Principal Investigator:

Charles W. Drescher

Woodland Memorial Hospital

Recruiting

Woodland, California, United States, 95695

Contacts

Site Public Contact

916-556-3301OncologyResearch@DignityHealth.org

Principal Investigator:

Shahzad Siddique

Penrose-Saint Francis Healthcare

Recruiting

Colorado Springs, Colorado, United States, 80907

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Rocky Mountain Cancer Centers-Penrose

Recruiting

Colorado Springs, Colorado, United States, 80907

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Saint Francis Cancer Center

Recruiting

Colorado Springs, Colorado, United States, 80923

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Porter Adventist Hospital

Recruiting

Denver, Colorado, United States, 80210

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Mercy Medical Center

Recruiting

Durango, Colorado, United States, 81301

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Southwest Oncology PC

Recruiting

Durango, Colorado, United States, 81301

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Saint Anthony Hospital

Recruiting

Lakewood, Colorado, United States, 80228

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Littleton Adventist Hospital

Recruiting

Littleton, Colorado, United States, 80122

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Longmont United Hospital

Recruiting

Longmont, Colorado, United States, 80501

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Parker Adventist Hospital

Recruiting

Parker, Colorado, United States, 80138

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Saint Mary Corwin Medical Center

Recruiting

Pueblo, Colorado, United States, 81004

Contacts

Site Public Contact

719-776-6550ResearchTracking@Centura.Org

Principal Investigator:

Shahzad Siddique

Smilow Cancer Hospital-Derby Care Center

Recruiting

Derby, Connecticut, United States, 06418

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center-Fairfield

Recruiting

Fairfield, Connecticut, United States, 06824

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center at Glastonbury

Recruiting

Glastonbury, Connecticut, United States, 06033

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center at Greenwich

Recruiting

Greenwich, Connecticut, United States, 06830

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center - Guilford

Recruiting

Guilford, Connecticut, United States, 06437

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center at Saint Francis

Recruiting

Hartford, Connecticut, United States, 06105

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Center/Yale-New Haven Hospital

Recruiting

New Haven, Connecticut, United States, 06510

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Yale University

Recruiting

New Haven, Connecticut, United States, 06520

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Yale-New Haven Hospital North Haven Medical Center

Recruiting

North Haven, Connecticut, United States, 06473

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center at Long Ridge

Recruiting

Stamford, Connecticut, United States, 06902

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital-Torrington Care Center

Recruiting

Torrington, Connecticut, United States, 06790

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center-Trumbull

Recruiting

Trumbull, Connecticut, United States, 06611

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital-Waterbury Care Center

Recruiting

Waterbury, Connecticut, United States, 06708

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Smilow Cancer Hospital Care Center - Waterford

Recruiting

Waterford, Connecticut, United States, 06385

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Saint Alphonsus Cancer Care Center-Boise

Recruiting

Boise, Idaho, United States, 83706

Contacts

Site Public Contact

734-712-3671stephanie.couch@stjoeshealth.org

Principal Investigator:

John M. Schallenkamp

Saint Luke's Cancer Institute - Boise

Recruiting

Boise, Idaho, United States, 83712

Contacts

Site Public Contact

208-381-2774eslinget@slhs.org

Principal Investigator:

Charles W. Drescher

Saint Alphonsus Cancer Care Center-Caldwell

Recruiting

Caldwell, Idaho, United States, 83605

Contacts

Site Public Contact

734-712-3671stephanie.couch@stjoeshealth.org

Principal Investigator:

John M. Schallenkamp

Kootenai Health - Coeur d'Alene

Recruiting

Coeur d'Alene, Idaho, United States, 83814

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Walter Knox Memorial Hospital

Recruiting

Emmett, Idaho, United States, 83617

Contacts

Site Public Contact

734-712-3671stephanie.couch@stjoeshealth.org

Principal Investigator:

John M. Schallenkamp

Saint Luke's Cancer Institute - Fruitland

Recruiting

Fruitland, Idaho, United States, 83619

Contacts

Site Public Contact

208-381-2774eslinget@slhs.org

Principal Investigator:

Charles W. Drescher

Idaho Urologic Institute-Meridian

Recruiting

Meridian, Idaho, United States, 83642

Contacts

Site Public Contact

734-712-3671stephanie.couch@stjoeshealth.org

Principal Investigator:

John M. Schallenkamp

Saint Luke's Cancer Institute - Meridian

Recruiting

Meridian, Idaho, United States, 83642

Contacts

Site Public Contact

208-381-2774eslinget@slhs.org

Principal Investigator:

Charles W. Drescher

Saint Luke's Cancer Institute - Nampa

Recruiting

Nampa, Idaho, United States, 83686

Contacts

Site Public Contact

208-381-2774eslinget@slhs.org

Principal Investigator:

Charles W. Drescher

Saint Alphonsus Cancer Care Center-Nampa

Recruiting

Nampa, Idaho, United States, 83687

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Kootenai Clinic Cancer Services - Post Falls

Recruiting

Post Falls, Idaho, United States, 83854

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Kootenai Cancer Clinic

Recruiting

Sandpoint, Idaho, United States, 83864

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Saint Luke's Cancer Institute - Twin Falls

Recruiting

Twin Falls, Idaho, United States, 83301

Contacts

Site Public Contact

208-381-2774eslinget@slhs.org

Principal Investigator:

Charles W. Drescher

NorthShore University HealthSystem-Evanston Hospital

Recruiting

Evanston, Illinois, United States, 60201

Contacts

Site Public Contact

847-570-2109

Principal Investigator:

Nicklas R. Pfanzelter

NorthShore University HealthSystem-Glenbrook Hospital

Recruiting

Glenview, Illinois, United States, 60026

Contacts

Site Public Contact

847-570-2109

Principal Investigator:

Nicklas R. Pfanzelter

NorthShore University HealthSystem-Highland Park Hospital

Recruiting

Highland Park, Illinois, United States, 60035

Contacts

Site Public Contact

847-570-2109

Principal Investigator:

Nicklas R. Pfanzelter

North Shore Medical Center

Recruiting

Skokie, Illinois, United States, 60076

Contacts

Site Public Contact

888-823-5923ctsucontact@westat.com

Principal Investigator:

Nicklas R. Pfanzelter

Alegent Health Mercy Hospital

Recruiting

Council Bluffs, Iowa, United States, 51503

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Flaget Memorial Hospital

Recruiting

Bardstown, Kentucky, United States, 40004

Contacts

Site Public Contact

859-629-7169ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Commonwealth Cancer Center-Corbin

Recruiting

Corbin, Kentucky, United States, 40701

Contacts

Site Public Contact

859-629-7169ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Saint Joseph Hospital

Recruiting

Lexington, Kentucky, United States, 40504

Contacts

Site Public Contact

protocols@swog.org

Principal Investigator:

Shahzad Siddique

Saint Joseph Radiation Oncology Resource Center

Recruiting

Lexington, Kentucky, United States, 40504

Contacts

Site Public Contact

859-629-7169ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Saint Joseph Hospital East

Recruiting

Lexington, Kentucky, United States, 40509

Contacts

Site Public Contact

859-629-7169ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Saint Joseph London

Recruiting

London, Kentucky, United States, 40741

Contacts

Site Public Contact

859-629-7169ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Saint Joseph Mount Sterling

Recruiting

Mount Sterling, Kentucky, United States, 40353

Contacts

Site Public Contact

protocols@swog.org

Principal Investigator:

Shahzad Siddique

LSU Healthcare Network / Metairie Multi-Specialty Clinic

Recruiting

Metairie, Louisiana, United States, 70006

Contacts

Site Public Contact

504-210-3539emede1@lsuhsc.edu

Principal Investigator:

Scott E. Delacroix

Louisiana State University Health Science Center

Recruiting

New Orleans, Louisiana, United States, 70112

Contacts

Site Public Contact

504-210-3539emede1@lsuhsc.edu

Principal Investigator:

Scott E. Delacroix

Community Hospital of Anaconda

Recruiting

Anaconda, Montana, United States, 59711

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Billings Clinic Cancer Center

Recruiting

Billings, Montana, United States, 59101

Contacts

Site Public Contact

800-996-2663research@billingsclinic.org

Principal Investigator:

John M. Schallenkamp

Bozeman Deaconess Hospital

Recruiting

Bozeman, Montana, United States, 59715

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Benefis Healthcare- Sletten Cancer Institute

Recruiting

Great Falls, Montana, United States, 59405

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Great Falls Clinic

Recruiting

Great Falls, Montana, United States, 59405

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Kalispell Regional Medical Center

Recruiting

Kalispell, Montana, United States, 59901

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Saint Patrick Hospital - Community Hospital

Recruiting

Missoula, Montana, United States, 59802

Contacts

Site Public Contact

406-327-3118amy.hanneman@providence.org

Principal Investigator:

Charles W. Drescher

CHI Health Good Samaritan

Recruiting

Kearney, Nebraska, United States, 68847

Contacts

Site Public Contact

308-865-7963ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Saint Elizabeth Regional Medical Center

Recruiting

Lincoln, Nebraska, United States, 68510

Contacts

Site Public Contact

855-313-2409ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Alegent Health Immanuel Medical Center

Recruiting

Omaha, Nebraska, United States, 68122

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Alegent Health Bergan Mercy Medical Center

Recruiting

Omaha, Nebraska, United States, 68124

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Alegent Health Lakeside Hospital

Recruiting

Omaha, Nebraska, United States, 68130

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Creighton University Medical Center

Recruiting

Omaha, Nebraska, United States, 68131

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Midlands Community Hospital

Recruiting

Papillion, Nebraska, United States, 68046

Contacts

Site Public Contact

402-717-1510ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Garnet Health Medical Center

Recruiting

Middletown, New York, United States, 10940

Contacts

Site Public Contact

845-333-1133jgerlach@garnethealth.org

Principal Investigator:

Jeffrey M. Stewart

Good Samaritan Hospital - Cincinnati

Recruiting

Cincinnati, Ohio, United States, 45220

Contacts

Site Public Contact

513-853-1300ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Bethesda North Hospital

Recruiting

Cincinnati, Ohio, United States, 45242

Contacts

Site Public Contact

513-853-1300ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

TriHealth Cancer Institute-Westside

Recruiting

Cincinnati, Ohio, United States, 45247

Contacts

Site Public Contact

513-853-1300ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

TriHealth Cancer Institute-Anderson

Recruiting

Cincinnati, Ohio, United States, 45255

Contacts

Site Public Contact

513-853-1300ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

University of Oklahoma Health Sciences Center

Recruiting

Oklahoma City, Oklahoma, United States, 73104

Contacts

Site Public Contact

405-271-8777ou-clinical-trials@ouhsc.edu

Principal Investigator:

Kelly L. Stratton

Saint Alphonsus Medical Center-Baker City

Recruiting

Baker City, Oregon, United States, 97814

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Saint Charles Health System

Recruiting

Bend, Oregon, United States, 97701

Contacts

Site Public Contact

541-706-2909nosall@stcharleshealthcare.org

Principal Investigator:

Charles W. Drescher

Clackamas Radiation Oncology Center

Recruiting

Clackamas, Oregon, United States, 97015

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Providence Cancer Institute Clackamas Clinic

Recruiting

Clackamas, Oregon, United States, 97015

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Bay Area Hospital

Recruiting

Coos Bay, Oregon, United States, 97420

Contacts

Site Public Contact

541-269-8392cherie.cox@bayareahospital.org

Principal Investigator:

Charles W. Drescher

Providence Newberg Medical Center

Recruiting

Newberg, Oregon, United States, 97132

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Saint Alphonsus Medical Center-Ontario

Recruiting

Ontario, Oregon, United States, 97914

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

Providence Willamette Falls Medical Center

Recruiting

Oregon City, Oregon, United States, 97045

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Providence Portland Medical Center

Recruiting

Portland, Oregon, United States, 97213

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Providence Saint Vincent Medical Center

Recruiting

Portland, Oregon, United States, 97225

Contacts

Site Public Contact

503-215-2614CanRsrchStudies@providence.org

Principal Investigator:

Charles W. Drescher

Oregon Health and Science University

Recruiting

Portland, Oregon, United States, 97239

Contacts

Site Public Contact

503-494-1080trials@ohsu.edu

Principal Investigator:

Alexandra O. Sokolova

Saint Charles Health System-Redmond

Recruiting

Redmond, Oregon, United States, 97756

Contacts

Site Public Contact

541-706-2909

Principal Investigator:

Charles W. Drescher

Smilow Cancer Hospital Care Center - Westerly

Recruiting

Westerly, Rhode Island, United States, 02891

Contacts

Site Public Contact

203-785-5702canceranswers@yale.edu

Principal Investigator:

Joseph W. Kim

Providence Regional Cancer System-Aberdeen

Recruiting

Aberdeen, Washington, United States, 98520

Contacts

Site Public Contact

360-412-8958deidre.dillon@providence.org

Principal Investigator:

Charles W. Drescher

PeaceHealth Saint Joseph Medical Center

Recruiting

Bellingham, Washington, United States, 98225

Contacts

Site Public Contact

360-788-8223

Principal Investigator:

Charles W. Drescher

Harrison Medical Center

Recruiting

Bremerton, Washington, United States, 98310

Contacts

Site Public Contact

253-426-6882ResearchInstituteInquiries@CommonSpirit.org

Principal Investigator:

Shahzad Siddique

Providence Regional Cancer System-Centralia

Recruiting

Centralia, Washington, United States, 98531

Contacts

Site Public Contact

360-412-8958deidre.dillon@providence.org

Principal Investigator:

Charles W. Drescher

Swedish Cancer Institute-Edmonds

Recruiting

Edmonds, Washington, United States, 98026

Contacts

Site Public Contact

206-215-3086PCRC-NCORP@Swedish.org

Principal Investigator:

Charles W. Drescher

Providence Regional Cancer Partnership

Recruiting

Everett, Washington, United States, 98201

Contacts

Site Public Contact

425-261-3529marilyn.birchman@providence.org

Principal Investigator:

Charles W. Drescher

Swedish Cancer Institute-Issaquah

Recruiting

Issaquah, Washington, United States, 98029

Contacts

Site Public Contact

206-215-3086PCRC-NCORP@Swedish.org

Principal Investigator:

Charles W. Drescher

Kadlec Clinic Hematology and Oncology

Recruiting

Kennewick, Washington, United States, 99336

Contacts

Site Public Contact

509-783-4637research@kadlecmed.org

Principal Investigator:

Charles W. Drescher

Providence Regional Cancer System-Lacey

Recruiting

Lacey, Washington, United States, 98503

Contacts

Site Public Contact

360-412-8958deidre.dillon@providence.org

Principal Investigator:

Charles W. Drescher

PeaceHealth Saint John Medical Center

Recruiting

Longview, Washington, United States, 98632

Contacts

Site Public Contact

360-514-2016kmakin-bond@peacehealth.org

Principal Investigator:

Charles W. Drescher

Swedish Medical Center-Ballard Campus

Recruiting

Seattle, Washington, United States, 98107

Contacts

Site Public Contact

206-215-3086PCRC-NCORP@Swedish.org

Principal Investigator:

Charles W. Drescher

FHCC South Lake Union

Recruiting

Seattle, Washington, United States, 98109

Contacts

Site Public Contact

800-804-8824

Principal Investigator:

Heather H. Cheng

Fred Hutchinson Cancer Research Center

Recruiting

Seattle, Washington, United States, 98109

Contacts

Site Public Contact

800-804-8824

Principal Investigator:

Heather H. Cheng

Swedish Medical Center-Cherry Hill

Recruiting

Seattle, Washington, United States, 98122-5711

Contacts

Site Public Contact

206-215-3086PCRC-NCORP@Swedish.org

Principal Investigator:

Charles W. Drescher

Swedish Medical Center-First Hill

Recruiting

Seattle, Washington, United States, 98122

Contacts

Site Public Contact

206-215-3086PCRC-NCORP@Swedish.org

Principal Investigator:

Charles W. Drescher

University of Washington Medical Center - Montlake

Recruiting

Seattle, Washington, United States, 98195

Contacts

Site Public Contact

800-804-8824

Principal Investigator:

Heather H. Cheng

PeaceHealth United General Medical Center

Recruiting

Sedro-Woolley, Washington, United States, 98284

Contacts

Site Public Contact

360-788-8238lkey@peacehealth.org

Principal Investigator:

Charles W. Drescher

Providence Regional Cancer System-Shelton

Recruiting

Shelton, Washington, United States, 98584

Contacts

Site Public Contact

360-412-8958deidre.dillon@providence.org

Principal Investigator:

Charles W. Drescher

PeaceHealth Southwest Medical Center

Recruiting

Vancouver, Washington, United States, 98664

Contacts

Site Public Contact

360-514-3940kmakin-bond@peacehealth.org

Principal Investigator:

Charles W. Drescher

Providence Saint Mary Regional Cancer Center

Recruiting

Walla Walla, Washington, United States, 99362

Contacts

Site Public Contact

509-897-5993Cheryl.Dodd@providence.org

Principal Investigator:

Charles W. Drescher

Providence Regional Cancer System-Yelm

Recruiting

Yelm, Washington, United States, 98597

Contacts

Site Public Contact

360-412-8958deidre.dillon@providence.org

Principal Investigator:

Charles W. Drescher

Billings Clinic-Cody

Recruiting

Cody, Wyoming, United States, 82414

Contacts

Site Public Contact

800-996-2663research@billingsclinic.org

Principal Investigator:

John M. Schallenkamp

Welch Cancer Center

Recruiting

Sheridan, Wyoming, United States, 82801

Contacts

Site Public Contact

406-969-6060mccinfo@mtcancer.org

Principal Investigator:

John M. Schallenkamp

More Information

Sponsor

SWOG Cancer Research Network

Last update posted

Jan 29, 2026

Last verified

Jan, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-08. This information was provided to ClinicalTrials.gov by SWOG Cancer Research Network on 2026-01-29.