Recruiting

Sleep Timing

Sponsor:

Stanford University

Code:

NCT05808179

Conditions

Sleep Insufficiency

Sleep

Adolescent Behavior

Eligibility Criteria

Sex: All

Age: 14 - 18

Healthy Volunteers: Accepted

Interventions

Light

CBT

Sham Light

Study Details

Brief summary:

The goal of this clinical trial is to determine whether a combination of a novel lighting intervention and a behavioral intervention are able to increase total sleep time in adolescents. The main questions this trial aims to answer are whether this combination therapy is able to meaningfully increase total sleep time in adolescents, and do so over a sustained period of time, and whether such a changes is associated with concomitant changes in mood and cognitive performance.

Conditions

Sleep Insufficiency

Sleep

Adolescent Behavior

Study ID

NCT05808179

Start date

Jul 1, 2022

Status verified date

Jun, 2025

Completion date

Jun 20, 2026

Anticipated

Primary completion date

Jun 20, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 14 - 18

Healthy Volunteers: Accepted

Inclusion Criteria:

1. Aged 14-18 and a full-time student in grades 9-12
2. Male or female
3. Willing and with a schedule permitting them to go to bed at an earlier time
4. Planning on sleeping at home in their bedroom for at least 75% of the study

Exclusion Criteria:

1. Currently taking any medications (including over-the-counter medications, e.g., melatonin) specifically for the treatment of sleep disorders
2. Sleep only in the prone (face-down) position

Study Design

Enrollment

160 participants

Anticipated

Allocation

Randomized

Intervention Model

Parallel Assignment

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Light + Cognitive Behavioral Therapy (CBT)

1 hour of light flashes (typical wake time - 75 min → typical wake time - 15 min) and cognitive behavioral therapy

active comparator: Sham light + CBT

1 hour of sham light flashes (one flash) and cognitive behavioral therapy

Interventions

Light

Broad-spectrum white light flashes are \~4000 lux, 2 msec long, occur every 20 s

CBT

Cognitive behavioral therapy including psychoeducation, sleep hygiene, stimulus control, activity scheduling, motivational interviewing

Sham Light

Broad-spectrum white light flashes are \~4000 lux, 2 msec long, occur once

Primary outcome measure

  • Total sleep time [ Time Frame: 20 weeks ]

Central Contacts and Locations

Central contacts

Jamie Zeitzer, PhD

6504935000jzeitzer@stanford.edu

Locations

Stanford University

Recruiting

Stanford, California, United States, 94305

Contacts

Denise Zhou

denisezh@stanford.edu

More Information

Sponsor

Stanford University

Last update posted

Jun 24, 2025

Last verified

Jun, 2025

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Stanford University on 2025-06-24.