Recruiting

Asthma CHAMPS

Sponsor:

Johns Hopkins University

Code:

NCT05814510

Conditions

Asthma in Children

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Interventions

Asthma CHAMPS full program

Asthma CHAMPS Wait List Control

Study Details

Brief summary:

The long-term goal is to implement an evidence-based asthma intervention based on the Center for Disease Control's recommended framework (EXHALE) within Baltimore City Public Schools (BCPS). As part of a stepped wedge pragmatic trial the investigators will:

1. Evaluate the effectiveness of a tailored implementation plan of Asthma CHAMPS in 32 Baltimore city elementary schools to reduce asthma disparities.
2. Conduct a pragmatic trail using a stepped wedge design to evaluate implementation of a school and home asthma intervention program to reduce asthma-related absences, healthcare utilization and exacerbations and improve asthma control, among children enrolled in 32 Baltimore City elementary schools.
3. Use qualitative methods (observation and semi structured interviews) to obtain stakeholder feedback (parents, community health workers, school personnel and administrators) on impact of Asthma CHAMPS, identify potential refinements in intervention and implementation strategies, and evaluate impact of local adaptation and fidelity on implementation success and sustainability.

Conditions

Asthma in Children

Study ID

NCT05814510

Start date

Nov 27, 2023

Status verified date

Aug, 2026

Completion date

Jun 30, 2027

Anticipated

Primary completion date

Jun 30, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0+

Healthy Volunteers: Accepted

Adult

Inclusion Criteria:

  • Aged 18 or older
  • Current caregiver of child with asthma or staff member at a Baltimore City K-8 Public School in Asthma CHAMPS

Exclusion Criteria:

  • Unwilling to consent

Children with asthma

Inclusion Criteria:

  • Asthma diagnosis
  • Currently enrolled in Baltimore City K-8 Public School participating in Asthma CHAMPS

Exclusion Criteria:

  • Unwilling to provide assent

Study Design

Enrollment

1000 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Other

Interventions and Outcome Measures

Arms

experimental: School staff

School staff in a K-8 school participating in Asthma CHAMPS

experimental: Children with asthma

Aged 5-13 and enrolled in Baltimore City Public School participating in Asthma CHAMPS

experimental: Caregivers of children with asthma

Caregiver of a child with asthma that is aged 5-13 enrolled in a Baltimore City Public School participating in Asthma CHAMPS

Interventions

Asthma CHAMPS full program

Full program includes (1) education for staff, students, and caregivers (2) environmental education and intervention (3) asthma care coordination (4) resources

Asthma CHAMPS Wait List Control

Stepped wedge design

Primary outcome measure

  • Asthma-related absences [ Time Frame: 4 years ]
  • Emergency Department (ED) utilization for asthma by children [ Time Frame: 4 years ]
  • Hospitalization for asthma by children [ Time Frame: 4 years ]
  • Oral corticosteroid steroid prescription for asthma by children [ Time Frame: 4 years ]

Central Contacts and Locations

Central contacts

Michelle N Eakin, PhD

410-550-0487meakin1@jhmi.edu

Meredith McCormack, MD MHS

mmccor16@jhmi.edu

Locations

Baltimore City Public Schools

Recruiting

Baltimore, Maryland, United States, 21202

More Information

Sponsor

Johns Hopkins University

Last update posted

Aug 10, 2026

Last verified

Aug, 2026

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Johns Hopkins University on 2026-08-10.