Recruiting

Virtual Reality Tool

Sponsor:

Medical University of South Carolina

Code:

NCT05816083

Conditions

Substance Use Disorders

HIV Infections

Eligibility Criteria

Sex: All

Age: 15 - 30

Healthy Volunteers: Accepted

Interventions

Virtual Reality Tool

Study Details

Brief summary:

This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance abuse risk behavior among at-risk young people who have experienced psychosocial trauma. Participants eligible for this study include young men who have sex with men (YMSM)/individuals who are romantically/physically attracted to men and adolescents with substance use disorder (SUD) between the ages of 15 - 30 and have experienced at least one traumatic event in their lifetime. Frontline healthcare workers who work within these populations are eligible for the study as well.

Conditions

Substance Use Disorders

HIV Infections

Study ID

NCT05816083

Start date

Feb 6, 2025

Status verified date

Sep, 2026

Completion date

Feb 28, 2027

Anticipated

Primary completion date

Dec 31, 2026

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 15 - 30

Healthy Volunteers: Accepted

Inclusion Criteria for YMSM are as follows:

  • Someone who identifies as a YMSM or identifies as someone with romantic or physical attraction to individuals who identify as men
  • Is aged 15-30 years
  • Have experienced at least one ITE in lifetime (i.e., sexual assault, physical assault, witnessed domestic or community violence)
  • Report being consensually sexually active or planning to become sexually active with a partner in the next 12 months
  • Live in the Charleston, SC/Tri-county area

Inclusion Criteria for adolescents with SUD are as follows:

  • Someone who reports using substances in the past year (for participants ages 15-17) or the past 6 months (for participants ages 18-30)
  • Is aged 15-30 years
  • Have experienced at least one ITE in lifetime (i.e., sexual assault, physical assault, witnessed domestic or community violence)
  • Report being consensually sexually active or planning to become sexually active with a partner in the next 12 months
  • Live in the Charleston, SC/Tri-county area

Inclusion Criteria for front line healthcare workers are as follows:

  • works directly with adolescents who have experienced ITE and/or
  • works directly with adolescents or young adults with SUD and/or
  • works directly with YMSM and/or
  • works directly with and/or adolescent or young adults who are HIV-positive

Exclusion Criteria for all participants are as follows:

  • exhibits psychotic symptoms;
  • exhibits significant cognitive disability;
  • reports a history of Pervasive Developmental Disorder;
  • has active suicidal or homicidal ideations
  • self-reports high levels of motion sickness

Study Design

Enrollment

50 participants

Anticipated

Intervention Model

Single group

Primary purpose

Treatment

Interventions and Outcome Measures

Arms

experimental: Virtual Reality

All participants will receive the same intervention

Interventions

Virtual Reality Tool

Virtual Reality Tool for At-Risk Trauma-Exposed Young People

Primary outcome measure

  • Quantity and Frequency of Substance Use [ Time Frame: Day 0 (Session 1) up to Day 14 (Session 3) ]

Central Contacts and Locations

Central contacts

Charli Kirby, BA

(843) 408-6140kirbych@musc.edu

Carla Danielson, PhD

danielso@musc.edu

Locations

National Crime Victims Research and Treatment Center

Recruiting

Charleston, South Carolina, United States, 29425

Contacts

Carla K Danielson, Ph.D.

danielso@musc.edu

More Information

Sponsor

Medical University of South Carolina

Last update posted

Sep 9, 2026

Last verified

Sep, 2026

Keywords

  • substance use disorders
  • alcohol use
  • substance use
  • HIV infections
  • HIV risk
  • virtual reality

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Medical University of South Carolina on 2026-09-09.