Recruiting

Environmental Exposure

Sponsor:

Purdue University

Code:

NCT05819996

Conditions

Vapors; Inhalation

Cancer

Volatile Organic Compounds

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Environmental educational campaign

Study Details

Brief summary:

Groundwater in Martinsville, IN, is contaminated by volatile organic compounds (VOCs), tetrachloroethylene (PCE) and trichloroethylene (TCE). Indoor air in some residential and commercial buildings is also contaminated with PCE and TCE. This study is being conducted to better understand the impact of low-level exposures to these compounds on community members' health. Data collected in this study will be used to help the community identify a course of action.

Conditions

Vapors; Inhalation

Cancer

Volatile Organic Compounds

Study ID

NCT05819996

Start date

Feb 17, 2023

Status verified date

May, 2024

Completion date

May 31, 2028

Anticipated

Primary completion date

May 31, 2028

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Inclusion Criteria:

  • Residents of Martinsville, Indiana
  • 18 years or older

Study Design

Enrollment

510 participants

Anticipated

Intervention Model

Single group

Primary purpose

Other

Interventions and Outcome Measures

Arms

other: Martinsville Residents

Residents of Martinsville, Indiana, will receive educational campaign promoting participation in environmental testing

Interventions

Environmental educational campaign

Educational campaign will be conducted to promote participation in indoor air testing.

Primary outcome measure

  • Change in concerns about environmental chemical contamination in Martinsville. [ Time Frame: For Measure 1a, Time frame is from year 1 to year 3; for Measure 1b, Time frame is from year 1 to year 5. ]
  • Changes in awareness of possible exposure to chemicals from soil or groundwater in Martinsville. [ Time Frame: For Measure 2a, Time frame is from year 1 to year 3; for Measure 2b, Time frame is from year 1 to year 5. ]
  • Change in willingness to have respondent's homes tested for chemical contamination from contaminated soil or groundwater. [ Time Frame: For Measure 3a, Time frame is from year 1 to year 3; for Measure 3b, Time frame is from year 1 to year 5. ]

Central Contacts and Locations

Central contacts

Sa Liu, MPH, PhD

765-496-6240saliu@purdue.edu

Locations

Purdue University

Recruiting

West Lafayette, Indiana, United States, 47907

Contacts

Sa Liu, PhD

7654966240saliu@purdue.edu

Monica M Bozymski, MS

765-496-4823mbozymsk@purdue.edu

More Information

Sponsor

Purdue University

Last update posted

Mar 18, 2025

Last verified

May, 2024

Keywords

  • Tetrachloroethylene
  • Trichloroethylene
  • PCE
  • TCE
  • Community environmental contamination
  • Chlorinated volatile organic compounds

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-10. This information was provided to ClinicalTrials.gov by Purdue University on 2025-03-18.