Recruiting

Influenza Vaccination

Sponsor:

University of Colorado, Denver

Code:

NCT05832307

Conditions

Influenza

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

Interventions

Existing Influenza Vaccination Practices

Standardized inpatient influenza vaccination program

Study Details

Brief summary:

This study plans to learn more about whether a stakeholder-informed, standardized inpatient vaccination program will increase influenza vaccination rates of hospitalized children across US pediatric health systems. The first part of the study is to form a multidisciplinary team of stakeholders, including parents, providers, nurses, pharmacists, informaticists, data analysts and communication experts across three sites in synthesizing a best practice implementation guide for an inpatient influenza vaccination program, which will then be piloted at these three sites.

Conditions

Influenza

Study ID

NCT05832307

Start date

Oct 31, 2024

Status verified date

Apr, 2026

Completion date

Jul 31, 2027

Anticipated

Primary completion date

Jul 31, 2027

Anticipated

Eligibility Criteria

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Accepted

Inclusion Criteria:

  • At least 6 months of age
  • Admitted to an inpatient unit at a participating health system

Exclusion:

\- Admission to critical care sites or hematology-oncology services

Exclusion Criteria:

  • At least 6 months of age
  • Admitted to an inpatient unit at a participating health system

Exclusion:

\- Admission to critical care sites or hematology-oncology services

Study Design

Enrollment

22000 participants

Anticipated

Allocation

Randomized

Intervention Model

Sequential

Primary purpose

Health Services Research

Interventions and Outcome Measures

Arms

active comparator: Standardized inpatient influenza vaccination program

Intervention A: The basic intervention is the inpatient influenza vaccination program, which will be comprised of the following core components: informatics and data analytic tools, evidenced-based education and communication, a multidisciplinary leadership team, and end-user engagement. Intervention B: The intensified intervention is the multifaceted influenza vaccination strategy (Intervention A) plus a learning collaborative with lead site facilitation during the trial period.

active comparator: Existing inpatient influenza vaccination practices

Usual care is defined as the inpatient influenza vaccination practices that currently exist at a given site.

Interventions

Existing Influenza Vaccination Practices

Usual care is defined as the existing inpatient influenza vaccination practices that currently exist at a given site.

Standardized inpatient influenza vaccination program

Intervention A: The basic intervention is the inpatient influenza vaccination program Intervention B: The intensified intervention is the multifaceted influenza vaccination strategy (Intervention A) plus a learning collaborative

Primary outcome measure

  • Vaccine administration rate [ Time Frame: 1 year ]

Central Contacts and Locations

Central contacts

Suchitra Rao

7207772823suchitra.rao@childrenscolorado.org

Locations

Ann and Robert Lurie's Children Hospital of Chicago

Recruiting

Chicago, Illinois, United States, 60611

Contacts

Ravi Jhaveri, MD

312-227-4080rjhaveri@luriechildrens.org

Principal Investigator:

Ravi Jhaveri, MD

Seattle Children's Hospital

Recruiting

Seattle, Washington, United States, 98105

Contacts

Annika Hofstetter, MD, PhD, MPH

205-884-1699annika.hofstetter@seattlechildrens.org

Principal Investigator:

Annika Hofstetter, MD, PhD, MPH

More Information

Sponsor

University of Colorado, Denver

Last update posted

Apr 8, 2026

Last verified

Apr, 2026

Keywords

  • vaccination
  • influenza

Trial information was received from ClinicalTrials.gov and was last updated on 2026-09-09. This information was provided to ClinicalTrials.gov by University of Colorado, Denver on 2026-04-08.